Fair Value of Financial Assets and Liabilities, Allocated into Level 1, Level 2, and Level 3 Measured on Recurring Basis (Detail) - USD ($) $ in Thousands	Mar. 31, 2017	Dec. 31, 2016
Financial Assets:
Total financial assets	$ 286,312	$ 195,289
Money market funds
Financial Assets:
Total financial assets	14,888	6,254
Corporate notes and commercial paper
Financial Assets:
Total financial assets	172,173	133,099
U.S. government agency securities
Financial Assets:
Total financial assets	99,251	55,936
Embedded derivative liabilities
Financial Liabilities:
Total financial liabilities	855	246
Fair Value, Inputs, Level 1
Financial Assets:
Total financial assets	14,888	6,254
Fair Value, Inputs, Level 1 | Money market funds
Financial Assets:
Total financial assets	14,888	6,254
Fair Value, Inputs, Level 2
Financial Assets:
Total financial assets	271,424	189,035
Fair Value, Inputs, Level 2 | Corporate notes and commercial paper
Financial Assets:
Total financial assets	172,173	133,099
Fair Value, Inputs, Level 2 | U.S. government agency securities
Financial Assets:
Total financial assets	99,251	55,936
Fair Value, Inputs, Level 3 | Embedded derivative liabilities
Financial Liabilities:
Total financial liabilities	$ 855	$ 246