Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Current assets:
Cash and cash equivalents	$ 188,480	$ 186,488
Short-term investments	130,291	257,713
Restricted cash (SRX Cardio)	178	341
Receivables from collaborators		1,000
Prepaid research and development	7,299	16,976
Prepaid expenses and other current assets	2,680	3,059
Total current assets	328,928	465,577
Property and equipment, net	6,143	6,243
Intangible asset	3,151	3,151
Long-term investments		15,960
Prepaid and other long-term assets	5,214	11,993
Total assets	343,436	502,924
Current liabilities:
Accounts payable	14,546	10,279
Accrued compensation and employee benefits	4,806	5,459
Accrued research and development	23,818	24,195
Accrued and other liabilities	1,696	2,826
Deferred revenue, current portion	20,798	8,387
Total current liabilities	65,664	51,146
Notes payable, long-term	50,061
Long term obligation to Collaborator	8,000
Deferred revenue, long-term	24,965	18,629
Other long-term liabilities	2,057	2,826
Total liabilities	150,747	72,601
Stockholders’ equity:
Preferred stock, $0.001 par value, 5,000,000 shares authorized; no shares issued and outstanding
Common stock, $0.001 par value, 100,000,000 shares authorized at December 31, 2016 and 2015; 56,544,218 shares and 56,359,515 shares issued and outstanding at December 31, 2016 and 2015, respectively	57	57
Additional paid-in capital	1,108,832	1,076,791
Accumulated deficit	(918,345)	(649,302)
Accumulated other comprehensive loss	(12)	(150)
Total Portola stockholders’ equity	190,532	427,396
Noncontrolling interest (SRX Cardio)	2,157	2,927
Total stockholders' equity	192,689	430,323
Total liabilities and stockholders’ equity	$ 343,436	$ 502,924