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Accrued and Other Liabilities (Detail) (USD $) In Thousands, unless otherwise specified	Mar. 31, 2015	Dec. 31, 2014
Payables And Accruals [Abstract]
Research and development related	$ 22,311	$ 12,545
Legal and accounting fees	646us-gaap_AccruedProfessionalFeesCurrent	354us-gaap_AccruedProfessionalFeesCurrent
Deferred rent	215us-gaap_DeferredRentCreditCurrent	127us-gaap_DeferredRentCreditCurrent
Commercial related	745
Other	844us-gaap_OtherLiabilitiesCurrent	940us-gaap_OtherLiabilitiesCurrent
Total accrued liabilities	$ 24,761	$ 13,966

Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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- Definition

Aggregate carrying amount of current liabilities (due within one year or within the normal operating cycle if longer) not separately disclosed in the balance sheet. Includes costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered and of liabilities not separately disclosed.

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