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Organization - Additional Information (Detail) (USD $)
In Millions, except Share data, unless otherwise specified
1 Months Ended 3 Months Ended
Mar. 31, 2015
Mar. 31, 2015
Segment
Organization And Nature Of Business [Line Items]    
Number of operating segment   1us-gaap_NumberOfOperatingSegments
Follow on offering price per share $ 40.00us-gaap_SaleOfStockPricePerShare $ 40.00us-gaap_SaleOfStockPricePerShare
Proceeds from offering and over-allotment option, net $ 108.4ptla_ProceedsFromIssuanceOfCommonStockNet  
Follow-on Offering    
Organization And Nature Of Business [Line Items]    
Stock issued during the period 2,870,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_SubsidiarySaleOfStockAxis
= ptla_FollowOnPublicOfferMember
 
Underwriting discounts, commissions and offering expenses, net $ 0.4ptla_UnderwritingDiscountsCommissionsAndOfferingExpensesRelatedToPublicOffering
/ us-gaap_SubsidiarySaleOfStockAxis
= ptla_FollowOnPublicOfferMember
 
Underwriters Overallotment Option    
Organization And Nature Of Business [Line Items]    
Stock issued during the period 374,348us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_SubsidiarySaleOfStockAxis
= ptla_UnderwritersOverallotmentOptionMember