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Employee Benefit Plan - Additional Information (Detail) (USD $)
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Compensation And Retirement Disclosure [Abstract]      
Defined contribution plan maximum annual employer matching contribution per employee $ 2,000ptla_DefinedContributionPlanMaximumAnnualEmployerMatchingContributionPerEmployee $ 500ptla_DefinedContributionPlanMaximumAnnualEmployerMatchingContributionPerEmployee $ 500ptla_DefinedContributionPlanMaximumAnnualEmployerMatchingContributionPerEmployee
Employee benefit plans, contribution expense $ 153,000us-gaap_DefinedContributionPlanCostRecognized $ 59,000us-gaap_DefinedContributionPlanCostRecognized $ 31,000us-gaap_DefinedContributionPlanCostRecognized