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Quarterly Financial Data (Tables)
12 Months Ended
Dec. 31, 2014
Quarterly Financial Information Disclosure [Abstract]  
Quarterly Financial Information

The following table presents certain unaudited quarterly financial information. This information has been prepared on the same basis as the audited consolidated financial statements and includes all adjustments (consisting only of normal recurring adjustments) necessary to present fairly the unaudited quarterly results of operations set forth herein.

 

 

 

2014

 

 

2013

 

 

 

Q1

 

 

Q2

 

 

Q3

 

 

Q4

 

 

Q1

 

 

Q2

 

 

Q3

 

 

Q4

 

Collaboration and license revenue

 

$

2,372

 

 

$

2,415

 

 

$

2,427

 

 

$

2,411

 

 

$

3,108

 

 

$

2,601

 

 

$

2,766

 

 

$

2,056

 

Operating expenses

 

$

(33,396

)

 

$

(33,920

)

 

$

(38,204

)

 

$

(41,671

)

 

$

(20,761

)

 

$

(24,541

)

 

$

(21,995

)

 

$

(27,412

)

Net loss

 

$

(30,726

)

 

$

(31,350

)

 

$

(35,793

)

 

$

(39,256

)

 

$

(18,142

)

 

$

(21,598

)

 

$

(18,550

)

 

$

(25,062

)

Net loss per share:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Basic and diluted

 

$

(0.75

)

 

$

(0.76

)

 

$

(0.86

)

 

$

(0.82

)

 

$

(12.94

)

 

$

(1.47

)

 

$

(0.53

)

 

$

(0.63

)