X0306 4 2018-08-21 0001269021 PORTOLA PHARMACEUTICALS INC PTLA 0001250409 BIRD JEFFREY W 755 PAGE MILL ROAD, SUITE A-200 PALO ALTO CA 94304-1005 1 Common Stock 2018-08-21 4 P 0 137563.0000 25.1708 A 196616.0000 I By Trust (Trustees) Common Stock 2018-08-22 4 P 0 202082.0000 26.0934 A 398698.0000 I By Trust (Trustees) Common Stock 2018-08-23 4 P 0 50355.0000 26.6470 A 449053.0000 I By Trust (Trustees) Common Stock 9000.0000 D Common Stock 45402.0000 I By Ltd Partnership (NEST) Common Stock 921610.0000 I By Ltd Partnership (SHV) The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $25.00 to $25.20, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote. Shares held by a trust of which the reporting person is a trustee. The reporting person disclaims beneficial ownership in these shares except as to the reporting person's pecuniary interest in the trust. The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $25.89 to $26.30, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $26.41 to $26.95, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote. The reporting person shares pecuniary interest in these shares with other individuals pursuant to a contractual relationship. The reporting person disclaims beneficial ownership in these shares except as to the reporting person's pecuniary interest in these shares. Shares held by a limited partnership of which the reporting person is a trustee of a trust which is the general partner. The reporting person disclaims beneficial ownership in these shares except as to the reporting person's pecuniary interest therein. Shares held by Sutter Hill Ventures, a California Limited Partnership. The reporting person is a managing director and member of the management committee of the general partner of Sutter Hill Ventures, a California Limited Partnership. The reporting person disclaims beneficial ownership in these shares except as to the reporting person's pecuniary interest therein. /s/ Robert Yin, by power of attorney 2018-08-23