X0306 4 2020-07-02 1 0001269021 PORTOLA PHARMACEUTICALS INC PTLA 0001302390 Wolff Henry Ward C/O PORTOLA PHARMACEUTICALS, INC. 270 EAST GRAND AVENUE, SUITE 22 SOUTH SAN FRANCISCO CA 94080 1 0 0 0 Common Stock 2020-07-02 4 D 0 17960 18.00 D 0 D Restricted Stock Units 2020-07-02 4 D 0 7281 18.00 D 0 D Stock Option (Right to Buy) 2020-07-02 4 D 0 59092 0.00 D Common Stock 59092 0 D Stock Options (Right to Buy) 7.00 2020-07-02 4 D 0 5520 11.00 D 2021-12-15 Common Stock 5520 0 D Stock Options (Right to Buy) 7.00 2020-07-02 4 D 0 5000 11.00 D 2022-09-01 Common Stock 5000 0 D Stock Options (Right to Buy) 17.94 2020-07-02 4 D 0 11377 0.06 D 2030-06-11 Common Stock 11377 0 D Pursuant to the Agreement and Plan of Merger, dated as of May 5, 2020, by and among Portola Pharmaceuticals, Inc. (the "Issuer"), Alexion Pharmaceuticals, Inc. ("Alexion") and Odyssey Merger Sub Inc. ("Merger Sub") (the "Merger Agreement"), on July 2, 2020, Merger Sub merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a direct, wholly owned subsidiary of Alexion (the "Merger"). At the effective time of the Merger (the "Effective Time"), these shares were canceled in exchange for $18.00 per share in cash, without interest and subject to any applicable withholding taxes. At the Effective Time, each restricted stock unit ("RSU") was accelerated and canceled as of immediately prior to, and contingent upon, the Effective Time, in exchange for the right to receive a cash amount equal to the product of (i) the number of shares deliverable under such RSU multiplied by (ii) $18.00. In connection with the Merger, these options were accelerated and canceled without payment. At the Effective Time, each of these unvested and outstanding options was accelerated, canceled and converted into the right to receive a cash amount equal to the product of (i) the number of shares that are subject to such options and (ii) $18.00 less the applicable exercise price per share of such options, subject to any applicable withholding or other taxes required by applicable law. /s/ Mike Ouimette, Attorney-in-fact 2020-07-02