X0306 4 2019-01-31 0 0001269021 PORTOLA PHARMACEUTICALS INC PTLA 0001766524 Koenig Sheldon L. C/O PORTOLA PHARMACEUTICALS, INC. 270 E. GRAND AVENUE SOUTH SAN FRANCISCO CA 94080 0 1 0 0 EVP, Chief Commercial Officer Common Stock 2019-01-31 4 A 0 25000 0.00 A 25000 D Stock Option (Right to Buy) 27.10 2019-01-31 4 A 0 125000 0.00 A 2029-01-30 Common Stock 125000 125000 D Grant of Restricted Stock Units ("RSUs") in consideration of services rendered. The RSUs vest in three equal annual installments on March 1, 2020, March 1, 2021 and March 1, 2022, subject to the Reporting Person's Continuous Service under the Issuer's plan documents as of each such date. The Options vest as follows: 25% of the shares will vest one year from the Vesting Commencement Date of January 28, 2019, and the remaining shares will vest ratably over the next 36 months. /s/ Mike Ouimette, as attorney-in-fact 2019-02-04