X0306 4 2018-10-31 0 0001269021 PORTOLA PHARMACEUTICALS INC PTLA 0001533228 Garland J. Scott C/O PORTOLA PHARMACEUTICALS, INC. 270 E. GRAND AVENUE SOUTH SAN FRANCISCO CA 94080 1 1 0 0 President and CEO Common Stock 2018-10-31 4 A 0 125000 0.00 A 125000 D Stock Option (Right to Buy) 19.69 2018-10-31 4 A 0 250000 0.00 A 2028-10-30 Common Stock 250000 250000 D Grant of Restricted Stock Units ("RSU") in consideration of services rendered. The RSUs will vest in equal annual installments on each of the first three anniversaries of the October 31, 2018 grant date, subject to Reporting Person's Continuous Service as of each such date. The Option vests as follows: 25% of the shares will vest one year from the Vesting Commencement Date of October 8, 2018, and the remaining shares shall vest ratably over the next 36 months. /s/ Mike Ouimette, as attorney-in-fact 2018-10-31