X0306 4 2018-01-31 0 0001269021 PORTOLA PHARMACEUTICALS INC PTLA 0001721090 Lawrence John H III C/O PORTOLA PHARMACEUTICALS, INC. 270 EAST GRAND AVENUE SOUTH SAN FRANCISCO CA 94080 0 1 0 0 SVP, Chief Medical Officer Common Stock 2018-01-31 4 A 0 6875 0.00 A 6875 D Stock Option (Right to Buy) 51.31 2018-01-31 4 A 0 27500 0.00 A 2028-01-30 Common Stock 27500 27500 D Grant of Restricted Stock Units ("RSU") in consideration of services rendered. The RSU vests annually over three years commencing on March 1, 2018, subject to Reporting Person's Continuous Service (as defined in the Issuer's 2013 Equity Incentive Plan) as of each such date. The option shall vest as follows: 1/48th of the shares subject to the option shall vest each month after January 1, 2018, subject to the Reporting Person's Continuous Service as of each such date. /s/Mike Ouimette, as attorney-in-fact 2018-02-02