X0306 4 2015-06-16 0 0001269021 PORTOLA PHARMACEUTICALS INC PTLA 0001187333 RENTON HOLLINGS C/O PORTOLA PHARMACEUTICALS, INC. 270 EAST GRAND AVE. SOUTH SAN FRANCISCO CA 94080 1 0 0 0 Stock Option (Right to Buy) 44.39 2015-06-16 4 A 0 10000 0.00 A 2025-06-16 Common Stock 10000 10000 D The option shares vest as follow: 1/12 of the shares subject to each option shall vest each month after June 16, 2015, subject to Reporting Person's Continuous Service (as defined in the Issuer's 2013 Equity Incentive Plan) as of each such date. /s/ Mike Ouimette, as attorney-in-fact 2015-06-17