X0306 4 2015-01-27 0 0001269021 PORTOLA PHARMACEUTICALS INC PTLA 0001574558 Lis William C/O PORTOLA PHARMACEUTICALS, INC. 270 EAST GRAND AVE. SOUTH SAN FRANCISCO CA 94080 1 1 0 0 Chief Executive Officer Common Stock 2015-01-27 4 A 0 27500 0.00 A 27500 D Stock Option (Right to Buy) 29.72 2015-01-27 4 A 0 130000 0.00 A 2025-01-26 Common Stock 130000 130000 D Performance Stock Unit 2015-01-27 4 A 0 70000 0.00 A 2019-01-27 Common Stock 70000 70000 D Grant of Restricted Stock Units ("RSU") in consideration of services rendered. The RSU vests annually over three years commencing on March 1, 2015, subject to Reporting Person's Continuous Service (as defined in the Issuer's 2013 Equity Incentive Plan) as of each such date. The Option shall vest as follows: 1/48th of the shares subject to the option shall vest each month after January 1, 2015, subject to the Reporting Person's Continuous Service as of each such date. Each Performance Stock Unit ("PSU") represents a contingent right to receive one share of Issuer's Common Stock. The PSU's vest as follow: half of the shares subject to each PSU will be earned when the average closing price of Issuer's stock on the NASDAQ Global Select Market is above $50.00 per share for 45 consecutive trading days, and an additional half of the shares will be earned when the average closing price of Issuer's stock is above $60.00 per share for 45 consecutive trading days. Any shares earned will then vest on the one year anniversary of the date such shares were earned, subject to Reporting Person's Continuous Service as of each such date. /s/ Mike Ouimette, as attorney-in-fact 2015-01-29