X0206 3 2013-05-21 0 0001269021 PORTOLA PHARMACEUTICALS INC PTLA 0001291804 George Jean C/O ADVANCED TECHNOLOGY VENTURES 500 BOYLSTON STREET, SUITE 1380 BOSTON MA 02116 1 0 0 0 Series B Convertible Preferred Stock Common Stock 37379 I Advanced Technology Ventures VII (B), L.P. Series B Convertible Preferred Stock Common Stock 17966 I Advanced Technology Ventures VII (C), L.P. Series B Convertible Preferred Stock Common Stock 931468 I Advanced Technology Ventures VII, L.P. Series B Convertible Preferred Stock Common Stock 5551 I ATV Entrepreneurs VII, L.P. Series C Convertible Preferred Stock Common Stock 17302 I Advanced Technology Ventures VII (B), L.P. Series C Convertible Preferred Stock Common Stock 8316 I Advanced Technology Ventures VII (C), L.P. Series C Convertible Preferred Stock Common Stock 431173 I Advanced Technology Ventures VII, L.P. Series C Convertible Preferred Stock Common Stock 2569 I ATV Entrepreneurs VII, L.P. Series D Convertible Preferred Stock Common Stock 3448 I Advanced Technology Ventures VII (B), L.P Series D Convertible Preferred Stock Common Stock 1657 I Advanced Technology Ventures VII (C), L.P. Series D Convertible Preferred Stock Common Stock 85939 I Advanced Technology Ventures VII, L.P. Series D Convertible Preferred Stock Common Stock 512 I ATV Entrepreneurs VII, L.P. The Series B Preferred Stock has no expiration date and is convertible at any time at the option of the holder and will automatically convert upon the closing of the Issuer's initial public offering, at a conversion ratio of 1 share of Common Stock for every 1 share of Series B Preferred Stock, for no additional consideration. The shares do not have an expiration date. Ms. George is a managing director of ATV Associates VII, LLC, the management company of the Entities affiliated with Advanced Technology Ventures, and shares voting and dispositive power over the shares held by the Entities affiliated with Advanced Technology Ventures. Ms. George disclaims beneficial ownership thereof except to the extent of her respective proportionate pecuniary interest in such shares. The Series C Preferred Stock has no expiration date and is convertible at any time at the option of the holder and will automatically convert upon the closing of the Issuer's initial public offering, at a conversion ratio of 1 share of Common Stock for every 1 share of Series C Preferred Stock, for no additional consideration. The Series D Preferred Stock has no expiration date and is convertible at any time at the option of the holder and will automatically convert upon the closing of the Issuer's initial public offering, at a conversion ratio of 1 share of Common Stock for every 1 share of Series D Preferred Stock, for no additional consideration. /s/ Sally A. Kay, as attorney-in-fact 2013-05-21