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Organization - Additional Information (Detail) (USD $)
1 Months Ended 6 Months Ended 12 Months Ended
May 31, 2013
Jun. 30, 2013
Segment
Dec. 31, 2012
Segment
Dec. 31, 2011
Organization And Nature Of Business [Line Items]        
Number of operating segment   1 1  
Accumulated deficit   $ (242,060,000) $ (202,320,000) $ (213,686,000)
Cash, cash equivalents and investments   235,200,000 137,400,000  
Common stock initial public offering 9,686,171      
Public offering price of the shares sold $ 14.50      
Proceeds from initial public offering before offering costs 131,000,000      
Underwriting discounts and commissions 9,400,000      
Offering expenses 5,200,000      
Proceeds from initial public offering, net of underwriters discount 125,800,000 131,027,000    
Accrued offering costs   $ 2,107,000 $ 1,506,000  
Number of preferred stock converted into common stock 24,026,797      
Underwriters Overallotment Option
       
Organization And Nature Of Business [Line Items]        
Common stock initial public offering 1,263,413