Balance Sheet Components (Tables)

6 Months Ended

12 Months Ended

Jun. 30, 2013

Dec. 31, 2012

Property and Equipment

Property and equipment consists of the following (in thousands):

	December 31,
	2011			2012
Computer equipment	$	442		$	515
Capitalized software		424			423
Equipment		2,934			3,224
Leasehold improvements		3,499			3,499
		7,299			7,661
Less accumulated depreciation and amortization		(3,411	)		(4,800	)
Property and equipment, net	$	3,888		$	2,861

Accrued Expenses

Accrued and other liabilities consist of the following (in thousands):

	December 31, 2012		June 30, 2013
Research and development related	$	4,217	$	12,461
Legal and accounting fees		507		523
Deferred rent		831		854
Foreign currency forward contracts		—		175
Deferred offering costs		1,506		2,107
Other		338		205
Total accrued and other liabilities	$	7,399	$	16,325

Accrued and other liabilities consist of the following (in thousands):

	December 31,
	2011		2012
Research and development related	$	2,451	$	4,217
Legal and accounting fees		399		1,523
Deferred rent		786		831
Other		398		828
Total accrued liabilities	$	4,034	$	7,399