X0306 4 2015-12-09 0 0001269021 PORTOLA PHARMACEUTICALS INC PTLA 0001379348 Fullerton Management Pte Ltd 60B ORCHARD ROAD #06-18, TOWER 2 THE ATRIUM@ORCHARD SINGAPORE U0 238891 SINGAPORE 0 0 1 0 0001021944 Temasek Holdings (Private) Ltd 60B ORCHARD ROAD #06-18, TOWER 2 THE ATRIUM@ORCHARD SINGAPORE U0 238891 SINGAPORE 0 0 1 0 Common stock 2015-12-09 4 P 0 750000 48.00 A 6583568 I See footnote Fullerton Management Pte Ltd ("FMPL") indirectly owns 6,583,568 shares of the Issuer's common stock ("Shares") through two indirect wholly-owned subsidiaries, V-Sciences Investments Pte Ltd ("V-Sciences") which owns 750,000 Shares and Maxwell (Mauritius) Pte Ltd ("Maxwell") which owns 5,833,568 Shares. V-Sciences is wholly-owned by Temasek Life Sciences Private Limited, which is wholly owned by FMPL. Maxwell is wholly-owned by Cairnhill Investments (Mauritius) Pte Ltd which is wholly owned by FMPL. FMPL is wholly-owned by Temasek Holdings (Private) Limited. Accordingly, each of FMPL and Temasek Holdings (Private) Limited, through the ownership described herein, may be deemed to beneficially own the shares of common stock owned by V-Sciences and Maxwell, collectively. /s/ Christina Choo, Authorised Signatory, Temasek Holdings (Private) Limited 2015-12-10 /s/ Cheong Kok Tim, Director, Fullerton Management Pte Ltd 2015-12-10