CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Revenue:
Federal contract revenue	$ 56	$ 1,891	$ 295	$ 10,753
Total revenue	8,541	7,338	24,276	23,799
Expenses:
Research and development	16,334	23,661	61,349	73,006
Selling, general and administrative	12,573	14,868	47,909	45,794
Restructuring Costs			1,950
Total expenses	29,621	38,984	113,413	119,847
Loss from operations	(21,080)	(31,646)	(89,137)	(96,048)
Interest income	598	1,895	3,169	6,366
Interest expense	(3,843)	(4,242)	(12,806)	(12,597)
Other income, net	100	1,021	52	1,105
Loss before income taxes	(24,225)	(32,972)	(98,722)	(101,174)
Benefit for income taxes				1,538
Net loss applicable to common shareholders	$ (24,225)	$ (32,972)	$ (98,722)	$ (99,636)
Per share information:
Net loss per share of common stock-basic (in dollar per share)	$ (0.42)	$ (0.61)	$ (1.73)	$ (1.89)
Net loss per share of common stock-diluted (in dollar per share)	$ (0.42)	$ (0.61)	$ (1.73)	$ (1.89)
Basic weighted average shares outstanding (in shares)	57,229,229	53,920,109	57,049,038	52,755,114
Diluted weighted average shares outstanding (in shares)	57,229,229	53,920,109	57,049,038	52,755,114
Other comprehensive income:
Unrealized gain (loss) on available-for-sale securities		$ 43	$ 20	$ (71)
Total comprehensive loss	$ (24,225)	(32,929)	(98,702)	(99,707)
Product revenue, net
Revenue:
Revenue	8,468	5,429	23,928	13,010
Expenses:
Cost of product revenue	714	455	2,205	1,047
Collaboration revenue
Revenue:
Revenue	$ 17	$ 18	$ 53	$ 36