Collaboration Revenue - Narrative (Details) $ in Thousands, € in Millions			1 Months Ended		3 Months Ended	9 Months Ended		12 Months Ended
	Jul. 30, 2021 USD ($)	Jul. 30, 2021 EUR (€) item	May 31, 2023 USD ($)	Dec. 31, 2022 USD ($) item	Sep. 30, 2023 USD ($)	Sep. 30, 2023 USD ($)	Sep. 30, 2022 USD ($)	Dec. 31, 2022 USD ($) item product
License and Collaboration Revenue
Contract liability				$ 0	$ 500	$ 500		$ 0
Net Contract Liability				16,285	17,105	17,105		16,285
Collaboration revenue
License and Collaboration Revenue
Collaboration revenue					18	36	$ 12,673
Collaboration Agreement with Orion
License and Collaboration Revenue
Upfront fee received	$ 29,600	€ 25.0
Number of days from receipt of the final report, in which the collaboration agreement may be terminated	90 days	90 days
Percentage of upfront fee which must be refunded in the event of termination		75.00%
Amount of payment receivable upon achievement of specific clinical and commercial achievements | €		€ 97.0
Term of collaboration agreement	10 years	10 years
Number of performance obligations | item		3
Collaboration revenue								12,700
Transaction Price				37,880	37,880	37,880		37,880
Contract liability				15,062	13,803	13,803		15,062
Net Contract Liability				9,983	10,339	10,339		9,983
Offset by contract asset				5,079	3,464	3,464		5,079
Incremental costs incurred in obtaining the agreement					2,000	2,000
Capitalized contract costs					900	900
Collaboration Agreement with Orion | Selling, general and administrative
License and Collaboration Revenue
Contract acquisition costs included in general and administrative expense						1,100
Collaboration Agreement with Orion | License Revenue
License and Collaboration Revenue
Transaction Price				21,660	21,660	21,660		21,660
Collaboration Agreement with Orion | Collaboration revenue
License and Collaboration Revenue
Transaction Price				12,700				12,700
Collaboration Agreement with Orion | Development and Regulatory Services
License and Collaboration Revenue
Amortization of transaction price as a reduction of research and development costs						1,200		1,100
Transaction Price				6,717	6,717	6,717		6,717
Contract liability				5,559	4,300	4,300		5,559
Collaboration Agreement with Orion | Supply of License Product
License and Collaboration Revenue
Transaction Price				9,503	9,503	9,503		9,503
Contract liability				$ 9,503	9,503	9,503		9,503
Collaboration Agreement with Tenacia
License and Collaboration Revenue
Upfront fee received								10,000
Aggregate amount								256,000
Milestone regulatory approvals								15,000
Aggregative sales based milestone								$ 241,000
Term of collaboration agreement								45 days
Number of performance obligations | item				2				2
Number of commitments represent distinct performance | item				2				2
Transaction Price				$ 10,000	10,000	10,000		$ 10,000
Contract liability				7,002	7,002	7,002		7,002
Net Contract Liability				6,302	6,302	6,302		6,302
Offset by contract asset				700	700	700		700
Incremental costs incurred in obtaining the agreement				1,000				1,000
Capitalized contract costs				700				$ 700
Cost of product revenue				200
Number of Selected Products to which milestone payments applicable | product								1
Collaboration Agreement with Tenacia | Selling, general and administrative
License and Collaboration Revenue
Contract acquisition costs included in general and administrative expense				100
Collaboration Agreement with Tenacia | License Revenue
License and Collaboration Revenue
Collaboration revenue					0	0
Transaction Price				2,998	2,998	2,998		$ 2,998
Collaboration Agreement with Tenacia | Collaboration revenue
License and Collaboration Revenue
Transaction Price					3,000	3,000
Collaboration Agreement with Tenacia | Supply of License Product
License and Collaboration Revenue
Transaction Price				7,002	7,002	7,002		7,002
Contract liability				$ 7,002	$ 7,002	7,002		$ 7,002
Biologix Distribution and Supply Agreement
License and Collaboration Revenue
Upfront fee received			$ 500
Biologix Distribution and Supply Agreement | Maximum
License and Collaboration Revenue
Collaboration revenue						$ 100