CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022
Cash flows from operating activities
Net (loss) income	$ (99,636)	$ 14,496
Adjustments to reconcile net loss to net cash used in operating activities:
Gain from sale of PRV, net of transaction costs		(107,375)
Depreciation and amortization	426	336
Amortization of debt issuance costs	1,659	1,133
Accretion of revenue interest financing debt	4,421
Amortization of discount on short-term investments	(995)
Stock-based compensation expense	11,638	11,091
Amortization of net contract asset/liability	(1,259)	(1,000)
Noncash lease expense	146	194
Noncash lease liability	300	252
Write off of fixed assets	61	169
Issuance of common stock for cost of license agreement		1,169
Unrealized loss on foreign currency transactions		930
Changes in operating assets and liabilities:
Refund liability		(22,163)
Net contract asset/liability	2,079	11,057
Prepaid expenses and other current assets, non-current assets, inventory and accounts receivable	(6,290)	(2,313)
Accounts payable and accrued expenses	(3,559)	1,052
Net cash used in operating activities	(91,009)	(90,972)
Cash flows from investing activities
Proceeds from sale of PRV, net of transaction costs		107,375
Proceeds from sale of property and equipment	9
Maturities of short-term investments	17,000
Purchases of short-term investments	(51,995)
Purchases of property and equipment	(85)	(1,682)
Net cash (used in) provided by investing activities	(35,071)	105,693
Cash flows from financing activities
Proceeds from exercise of stock options	783	1,763
Proceeds from notes payable, net of fees		28,838
Payments of revenue interesting financing debt	(737)
Proceeds from equity offerings, net of offering costs	25,920
Net cash provided by financing activities	25,966	30,601
Net (decrease) increase in cash and cash equivalents	(100,114)	45,322
Cash and cash equivalents-beginning of period	240,551	122,927
Cash and cash equivalents-end of period	140,437	168,249
Supplemental disclosure of cash flow information
Unrealized loss on short-term investments	(71)
Financing costs	97
Cash paid for interest during the period	6,540
Cash paid for income taxes during the period	$ 903
Property and equipment in deposits placed in service		$ 1,665