Collaboration Revenue - Allocation of the transaction price to the performance obligations (Details) - USD ($) $ in Thousands	Jun. 30, 2023	Dec. 31, 2022
License and Collaboration Revenue
Net Contract Liability	$ 17,016	$ 16,285
Collaboration Agreement with Orion
License and Collaboration Revenue
Transaction Price	37,880	37,880
Cumulative Collaboration Revenue Recognized	23,655	22,818
Contract Liability	14,225	15,062
Less Total Contract Asset	3,992	5,079
Net Contract Liability	10,233	9,983
Collaboration Agreement with Orion | License Revenue
License and Collaboration Revenue
Transaction Price	21,660	21,660
Cumulative Collaboration Revenue Recognized	21,660	21,660
Collaboration Agreement with Orion | Development and Regulatory Services
License and Collaboration Revenue
Transaction Price	6,717	6,717
Cumulative Collaboration Revenue Recognized	1,995	1,158
Contract Liability	4,722	5,559
Collaboration Agreement with Orion | Supply of License Product
License and Collaboration Revenue
Transaction Price	9,503	9,503
Contract Liability	9,503	9,503
Collaboration Agreement with Tenacia
License and Collaboration Revenue
Transaction Price	10,000	10,000
Cumulative Collaboration Revenue Recognized	2,998	2,998
Contract Liability	7,002	7,002
Less Total Contract Asset	700	700
Net Contract Liability	6,302	6,302
Collaboration Agreement with Tenacia | License Revenue
License and Collaboration Revenue
Transaction Price	2,998	2,998
Cumulative Collaboration Revenue Recognized	2,998	2,998
Collaboration Agreement with Tenacia | Supply of License Product
License and Collaboration Revenue
Transaction Price	7,002	7,002
Contract Liability	$ 7,002	$ 7,002