Collaboration Revenue - Allocation of the transaction price to the performance obligations (Details) $ in Thousands, € in Millions			9 Months Ended	12 Months Ended
	Jul. 30, 2021 USD ($) item	Jul. 30, 2021 EUR (€) item	Sep. 30, 2022 USD ($)	Dec. 31, 2021 USD ($)	Sep. 30, 2022 EUR (€)	Jul. 31, 2021 USD ($)
License and Collaboration Revenue
Contract Liability			$ 15,114	$ 6,624
Less Total Contract Asset			5,615	7,181
Net Contract Asset				557
Net Contract Liability			9,499
Development and Regulatory Services
License and Collaboration Revenue
Contract Liability			5,611	2,681
Supply of License Product
License and Collaboration Revenue
Contract Liability			9,503	3,943
Collaboration Agreement with Orion
License and Collaboration Revenue
Number of performance obligations | item	3	3
Refundable portion of the upfront payment			21,200		€ 18.8
Transaction Price			37,880	15,717
Cumulative Collaboration Revenue Recognized			22,766	9,093
Contract Liability			15,100	6,600
Less Total Contract Asset			5,600	7,200
Net Contract Asset				600
Net Contract Liability			9,500
Incremental costs incurred in obtaining the agreement			2,000
Capitalized contract costs			900
Upfront fee received	$ 29,600	€ 25.0
Collaboration Agreement with Orion | Selling, general and administrative
License and Collaboration Revenue
Contract acquisition costs included in general and administrative expense			1,100
Collaboration Agreement with Orion | License Revenue
License and Collaboration Revenue
Transaction Price			21,660	8,987		$ 9,000
Cumulative Collaboration Revenue Recognized			21,660	8,987
Collaboration Agreement with Orion | Development and Regulatory Services
License and Collaboration Revenue
Amortization of transaction price as a reduction of research and development costs			1,100	100
Transaction Price			6,717	2,787
Cumulative Collaboration Revenue Recognized			1,106	106
Collaboration Agreement with Orion | Supply of License Product
License and Collaboration Revenue
Transaction Price			$ 9,503	$ 3,943