Collaboration Revenue - Narrative (Details) $ in Thousands, € in Millions			3 Months Ended
	Jul. 30, 2021 USD ($)	Jul. 30, 2021 EUR (€)	Mar. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)	Jul. 31, 2021 USD ($)
License and Collaboration Revenue
Collaboration revenue			$ 12,673
Contract with Customer, Contract Liability Net of Contract Asset			9,113
Less Total Contract Asset			6,626	$ 7,181
Collaboration Agreement with Orion
License and Collaboration Revenue
Upfront fee received	$ 29,600	€ 25.0
Number of days from receipt of the final report, in which the collaboration agreement may be terminated	90 days	90 days
Percentage of upfront fee which must be refunded in the event of termination		75.00%
Amount of payment receivable upon achievement of specific clinical and commercial achievements | €		€ 97.0
Term of collaboration agreement	10 years	10 years
Collaboration revenue			12,700
Contract with Customer, Refund Liability, Noncurrent			9,500
Transaction Price			37,880	15,717	$ 9,000
Contract with Customer, Contract Liability Net of Contract Asset			9,100
Less Total Contract Asset			$ 6,600	$ 7,200