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Commitments and Contingencies (Details)
$ in Thousands
1 Months Ended 12 Months Ended
Dec. 31, 2015
ft²
Nov. 30, 2015
ft²
item
Oct. 31, 2014
ft²
Dec. 31, 2017
USD ($)
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
ft²
Leases            
Operating lease agreement term   1 year 5 years      
Rental square feet office space | ft²   1,000 4,000      
Number of operating lease annual renewal options | item   2        
Term of annual renewal options   1 year        
Rent expense under operating lease       $ 300 $ 300 $ 100
Annual future minimum lease payments            
2018       340    
2019       324    
2020       330    
2021       139    
Total minimum lease payments       $ 1,133    
Employee Benefit Plan            
Maximum employees contribution (as a percent)       50.00%    
Vesting period       4 years    
Amended Lease            
Leases            
Operating lease agreement term 62 months          
Rental square feet office space | ft² 8,500         8,500
License Agreement | Purdue Neuroscience Company            
License agreement            
Expiration period of obligation to pay royalties       10 years