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Stockholders' Equity - Incentive Plans (Details) - shares
Jan. 01, 2018
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Stock options          
Stock option and incentive plans          
Outstanding (in shares)   3,754,320 2,239,044 1,799,226 1,670,574
2005 Plan          
Stock option and incentive plans          
Common stock reserved for issuance (in shares)   0      
2005 Plan | Stock options          
Stock option and incentive plans          
Outstanding (in shares)   364,420      
2014 Plan          
Stock option and incentive plans          
Common stock reserved for issuance (in shares) 2,187,100 187,100      
2014 Plan | Stock options          
Stock option and incentive plans          
Outstanding (in shares)   3,389,900      
2014 Plan | Restricted stock          
Stock option and incentive plans          
Outstanding (in shares)   239,800