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Organization and Description of the Business (Details) - USD ($)
$ in Thousands
3 Months Ended
Sep. 30, 2017
Dec. 31, 2017
Dec. 31, 2016
Liquidity      
Accumulated deficit   $ (144,727) $ (125,829)
Secondary public offering      
Liquidity      
Issuance of common stock in connection with secondary public offering (in shares) 10,733,334    
Proceeds from issuance of common stock, net of issuance costs $ 37,700