Description of the Business and Liquidity (Details) $ in Thousands	3 Months Ended
	Dec. 31, 2015 USD ($) shares	Sep. 30, 2016 USD ($) item
Number of dose forms for modulator | item		3
Liquidity
Accumulated deficit	$ (97,186)	$ (119,814)
Common Stock | Secondary public offering
Liquidity
Common stock issued (in shares) | shares	5,056,003
Proceeds from issuance of common stock, net of issuance costs	$ 28,100