Quarterly Financial Information (unaudited) (Tables)

12 Months Ended

Dec. 31, 2015

Quarterly Financial Information (unaudited)

Schedule of Quarterly financial information

		First Quarter		Second Quarter		Third Quarter		Fourth Quarter		Total Year
2015
Research and development expenses	$	5,468	$	3,915	$	3,472	$	6,061	$	18,916
General and administrative expenses	$	1,447	$	1,255	$	1,378	$	1,436	$	5,516
Net loss and net loss applicable to common stockholders	$	(7,007)	$	(5,273)	$	(4,963)	$	(7,607)	$	(24,850)
Net loss per share, basic and diluted	$	(0.50)	$	(0.37)	$	(0.35)	$	(0.45)	$	(1.67)
2014
Research and development expenses	$	2,149	$	2,805	$	1,569	$	2,167	$	8,690
General and administrative expenses	$	517	$	458	$	868	$	1,387	$	3,230
Net loss	$	(2,235)	$	(3,323)	$	(1,668)	$	(3,607)	$	(10,833)
Cumulative preferred stock dividends	$	(1,071)	$	(1,102)	$	(372)	$	-	$	(2,545)
Net loss applicable to common stockholders	$	(3,306)	$	(4,425)	$	(2,040)	$	(3,607)	$	(13,378)
Net loss per share, basic and diluted	$	(7.09)	$	(7.98)	$	(0.22)	$	(0.26)	$	(2.17)