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--12-31
FY
2014
2014-12-31
10-K
0001267813
14199666
Yes
Smaller Reporting Company
51500000
MARINUS PHARMACEUTICALS INC
No
No
P8Y
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Clinical Trial Expense Accruals</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">As part of the process of preparing our financial statements, we are required to estimate our expenses resulting from our obligations under contracts with vendors, clinical research organizations and consultants and under clinical site agreements in connection with conducting clinical trials. The financial terms of these contracts are subject to negotiations, which vary from contract to contract and may result in payment flows that do not match the periods over which materials or services are provided under such contracts. Our objective is to reflect the appropriate trial expenses in our financial statements by matching those expenses with the period in which services are performed and efforts are expended. We account for these expenses according to the progress of the trial as measured by patient progression and the timing of various aspects of the trial. We determine accrual estimates through financial models taking into account discussion with applicable personnel and outside service providers as to the progress or state of consummation of trials. During the course of a clinical trial, we adjust our clinical expense recognition if actual results differ from its estimates. We make estimates of our accrued expenses as of each balance sheet date based on the facts and circumstances known at that time. Our clinical trial accruals are dependent upon the timely and accurate reporting of contract research organizations and other third-party vendors. Although we do not expect our estimates to be materially different from amounts actually incurred, our understanding of the status and timing of services performed relative to the actual status and timing of services performed may vary and may result in reporting amounts that are too high or too low for any particular period. For the years ended December 31, 2014 and 2013, there were no material adjustments to our prior period estimates of accrued expenses for clinical trials.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
73000
777000
P10Y
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">7. Convertible Preferred Stock</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In June 2013, we issued 6,396,065 shares of Series C Preferred Stock at $1.1845 per share for proceeds of $7.5 million, net of issuance costs of $46 thousand. In addition, we issued 2,330,955 shares of Series C Preferred Stock from the conversion of the remaining outstanding $2.8 million in Series C Convertible Notes, including related accrued interest of $461 thousand. In April 2014, we issued 422,119 shares of Series C Preferred Stock. Proceeds of $500 thousand related to this issuance were received in 2013 and were reflected as an investor deposit in accrued expenses on the balance sheet as of December 31, 2013.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In connection with the closing our initial public offering during the third quarter of 2014, all outstanding shares of convertible preferred stock were converted to 7,661,871 shares of common stock.</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
2800000
P6M
25859000
29795000
P4Y
0.007
0.000
0.65
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Fair Value of Financial Instruments and Credit Risk</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">At December 31, 2014 and 2013, our financial instruments included cash and cash equivalents, accounts payable, accrued expenses, notes payable and derivative liabilities. The carrying amount of cash and cash equivalents, accounts payable and accrued expenses approximated fair value, given their short-term nature. The carrying amount of our notes payable approximate fair value because the interest rates on these instruments are reflective of rates that we could obtain on debt with similar terms and conditions. The carrying value of the derivative liabilities was the estimated fair value of the liability as more fully described below.</font>
</p>
<p style="margin:0pt;text-align:center;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Cash and cash equivalents subject us to concentrations of credit risk. However, we invest our cash in accordance with a policy objective that seeks to ensure both liquidity and safety of principal. The policy limits investments to instruments issued by the U.S. government and certain SEC-registered money market funds that invest only in U.S. government obligations and places restrictions on portfolio maturity terms.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
500000
0.0417
500000
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Recapitalization</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Our board of directors and stockholders approved a reverse stock split of our common stock at a ratio of one share for every six and one-half shares previously held. The reverse stock split was effected on July 16, 2014. All common stock share and per-share data included in these financial statements reflect the reverse stock split. In addition, the board of directors approved an increase in the authorized shares of our common stock to 100,000,000 shares.</font>
</p>
<p><font size="1"> </font></p>
</div> </div>
28000
2000
46000
4862000
220
8727020
6396065
422119
422119
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">5. Accrued Expenses</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">At December 31, 2014 and 2013, accrued expenses consisted of the following (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 80.00%;margin-left:54pt;">
<tr>
<td valign="bottom" style="width:62.52%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="5" valign="bottom" style="width:33.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:01.24%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:62.52%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.24%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.52%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Investor deposit </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>500
</td>
<td valign="bottom" style="width:01.24%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.52%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Payroll and related costs </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>419
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>204
</td>
<td valign="bottom" style="width:01.24%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.52%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Clinical trials and drug development </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>777
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>73
</td>
<td valign="bottom" style="width:01.24%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.52%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Professional fees </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>186
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>295
</td>
<td valign="bottom" style="width:01.24%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.52%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Other </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>121
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>24
</td>
<td valign="bottom" style="width:01.24%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:62.52%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,503
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,096
</td>
<td valign="bottom" style="width:01.24%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Investor deposit represents funds received from an investor for 422,119 shares of Series C Preferred Stock. The shares were issued in April 2014.</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
78000
536000
1096000
1503000
295000
186000
429000
356000
1121000
113476000
236000
236000
698000
698000
236000
221000
15000
698000
561000
137000
-4000
9160161
7596927
1093208
470026
1670574
1670574
11824000
50213000
11799000
50148000
9251000
9251000
48960000
48960000
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">2. Summary of Significant Accounting Policies</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Use of Estimates</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The preparation of financial statements in conformity with generally accepted accounting principles (GAAP) requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from such estimates.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Recapitalization</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Our board of directors and stockholders approved a reverse stock split of our common stock at a ratio of one share for every six and one-half shares previously held. The reverse stock split was effected on July 16, 2014. All common stock share and per-share data included in these financial statements reflect the reverse stock split. In addition, the board of directors approved an increase in the authorized shares of our common stock to 100,000,000 shares.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Fair Value of Financial Instruments and Credit Risk</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">At December 31, 2014 and 2013, our financial instruments included cash and cash equivalents, accounts payable, accrued expenses, notes payable and derivative liabilities. The carrying amount of cash and cash equivalents, accounts payable and accrued expenses approximated fair value, given their short-term nature. The carrying amount of our notes payable approximate fair value because the interest rates on these instruments are reflective of rates that we could obtain on debt with similar terms and conditions. The carrying value of the derivative liabilities was the estimated fair value of the liability as more fully described below.</font>
</p>
<p style="margin:0pt;text-align:center;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Cash and cash equivalents subject us to concentrations of credit risk. However, we invest our cash in accordance with a policy objective that seeks to ensure both liquidity and safety of principal. The policy limits investments to instruments issued by the U.S. government and certain SEC-registered money market funds that invest only in U.S. government obligations and places restrictions on portfolio maturity terms.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Cash and Cash Equivalents</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We consider all highly liquid investments that have maturities of three months or less when acquired to be cash equivalents. As of December 31, 2014 and 2013, we invested a portion of our cash balances in money market investments, which we have included as cash equivalents on our balance sheets.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Property and Equipment</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Property and equipment consist of laboratory and office equipment and are recorded at cost. Property and equipment are depreciated on a straight-line basis over their estimated useful lives. We estimate a life of three years for computer equipment, including software, and five years for laboratory equipment, office equipment, and furniture. When property and equipment are sold or otherwise disposed of, the cost and related accumulated depreciation are removed from the accounts and the resulting gain or loss is included in operating expenses.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Impairment of Long-Lived Assets</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We review long-lived assets, including property and equipment, for impairment whenever events or changes in business circumstances indicate that the carrying amount of an asset may not be fully recoverable. If the estimated undiscounted future cash flows expected to result from the use of the asset and its eventual disposition is less than its carrying amount an impairment loss would be recognized if the carrying value of the asset exceeded its fair value. Fair value is generally determined using discounted cash flows. Through December 31, 2014, no impairment has occurred.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Research and Development</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Research and development costs are expensed as incurred. Costs for certain development activities, such as clinical trials, are recognized based on an evaluation of the progress to completion of specific tasks using data such as subject enrollment, clinical site activations, or information provided to us by our vendors with respect to their actual costs incurred. Payments for these activities are based on the terms of the individual arrangements, which may differ from the pattern of costs incurred, and are reflected in the financial statements as prepaid or accrued research and development expense, as the case may be.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Income Taxes</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We recognize deferred tax assets and liabilities for temporary differences between the financial reporting basis and the tax basis of our assets and liabilities and the expected benefits of net operating loss carryforwards. The impact of changes in tax rates and laws on deferred taxes, if any, applied during the years in which temporary differences are expected to be settled, is reflected in the financial statements in the period of enactment. The measurement of deferred tax assets is reduced, if necessary, if, based on weight of the evidence, it is more likely than not that some, or all, of the deferred tax assets will not be realized. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in the period that such tax rate changes are enacted. At December 31, 2014 and 2013, we have concluded that a full valuation allowance is necessary for our net deferred tax assets. We had no material amounts recorded for uncertain tax positions, interest or penalties in the accompanying consolidated financial statements.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Loss Per Share of Common Stock</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Basic loss per share is computed by dividing net loss applicable to common stockholders by the weighted average number of shares of common stock outstanding during each period. Diluted loss per share includes the effect, if any, from the potential exercise or conversion of securities, such as convertible preferred stock, convertible notes payable, warrants, stock options, and unvested restricted stock, which would result in the issuance of incremental shares of common stock. In computing the basic and diluted net loss per share applicable to common stockholders, the weighted average number of shares remains the same for both calculations due to the fact that when a net loss exists, dilutive shares are not included in the calculation. These potentially dilutive securities are more fully described in Note 7.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The following table sets forth the computation of basic and diluted earnings per share for the years ended December 31, 2014 and 2013 (in thousands, except share and per share amounts):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 73.00%;margin-left:72pt;">
<tr>
<td valign="bottom" style="width:59.10%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="5" valign="bottom" style="width:36.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Year Ended December 31,</font></p>
</td>
<td valign="bottom" style="width:01.38%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:59.10%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.38%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.10%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Basic and diluted net loss per share of common stock:</font></p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.38%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.10%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(10,833
</td>
<td valign="bottom" style="width:03.40%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5,270
</td>
<td valign="bottom" style="width:01.38%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.10%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Dividends on Series B and C Preferred Stock </font></p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,545
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,804
</td>
<td valign="bottom" style="width:01.38%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.10%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss applicable to common stockholders </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(13,378
</td>
<td valign="bottom" style="width:03.40%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(9,074
</td>
<td valign="bottom" style="width:01.38%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.10%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Weighted average shares of common stock outstanding </font></p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6,152,669
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>462,972
</td>
<td valign="bottom" style="width:01.38%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.10%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss per share of common stock—basic and diluted </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2.17
</td>
<td valign="bottom" style="width:03.40%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(19.60
</td>
<td valign="bottom" style="width:01.38%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The following potentially dilutive securities outstanding at December 31, 2014 and 2013 have been excluded from the computation of diluted weighted average shares outstanding, as they would be antidilutive:</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 80.00%;margin-left:54pt;">
<tr>
<td valign="bottom" style="width:62.48%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="3" valign="bottom" style="width:33.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:62.48%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Convertible preferred stock </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>7,596,927
</td>
<td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Warrants </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>470,026
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Stock options </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,670,574
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,093,208
</td>
<td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,670,574
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>9,160,161
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Comprehensive Loss</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Comprehensive loss is defined as the change in equity of a business enterprise during a period from transactions and other events and circumstances from non-owner sources. Comprehensive loss was equal to net loss for all periods presented.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Segment Information</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Operating segments are defined as components of an enterprise about which separate discrete information is available for evaluation by the chief operating decision maker, or decision-making group, in deciding how to allocate resources and in assessing performance. We view our operations and manage our business in one segment, which is the identification and development of neuropsychiatric therapeutics.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Stock-Based Compensation</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We account for stock-based compensation in accordance with the provisions of Accounting Standards Codification (ASC) Topic 718, Compensation—Stock Compensation, or ASC 718, which requires the recognition of expense related to the fair value of stock-based awards in the statements of operations. For stock options issued to employees and members of our board of directors for their services on our board of directors, we estimate the grant-date fair value of options using the Black-Scholes option pricing model. The use of the Black-Scholes option pricing model requires management to make assumptions with respect to the expected term of the option, the expected volatility of the common stock consistent with the expected life of the option, risk-free interest rates, and the value of the common stock. For awards subject to time-based vesting, we recognize stock-based compensation expense, net of estimated forfeitures, on a straight-line basis over the requisite service period, which is generally the vesting term of the award. For awards subject to performance-based vesting conditions, we recognize stock-based compensation expense when it is probable that the performance condition will be achieved. Stock-based awards issued to non-employees are recorded at their fair values, and are periodically revalued as the equity instruments vest and are recognized as expense over the related service period in accordance with the provisions of ASC 718 and ASC Topic 505, Equity.</font>
</p>
<p style="margin:0pt;text-align:center;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Clinical Trial Expense Accruals</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">As part of the process of preparing our financial statements, we are required to estimate our expenses resulting from our obligations under contracts with vendors, clinical research organizations and consultants and under clinical site agreements in connection with conducting clinical trials. The financial terms of these contracts are subject to negotiations, which vary from contract to contract and may result in payment flows that do not match the periods over which materials or services are provided under such contracts. Our objective is to reflect the appropriate trial expenses in our financial statements by matching those expenses with the period in which services are performed and efforts are expended. We account for these expenses according to the progress of the trial as measured by patient progression and the timing of various aspects of the trial. We determine accrual estimates through financial models taking into account discussion with applicable personnel and outside service providers as to the progress or state of consummation of trials. During the course of a clinical trial, we adjust our clinical expense recognition if actual results differ from its estimates. We make estimates of our accrued expenses as of each balance sheet date based on the facts and circumstances known at that time. Our clinical trial accruals are dependent upon the timely and accurate reporting of contract research organizations and other third-party vendors. Although we do not expect our estimates to be materially different from amounts actually incurred, our understanding of the status and timing of services performed relative to the actual status and timing of services performed may vary and may result in reporting amounts that are too high or too low for any particular period. For the years ended December 31, 2014 and 2013, there were no material adjustments to our prior period estimates of accrued expenses for clinical trials.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Recent Accounting Pronouncements</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In June 2014, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update (ASU) No. 2014-10, </font><font style="display: inline;font-style:italic;">Elimination of Certain Financial Reporting Requirements, Including an Amendment to Variable Interest Entities Guidance in Topic 810, Consolidation</font><font style="display: inline;">, which eliminates all incremental financial reporting requirements for development stage entities by removing Accounting Standards Codification (ASC) Topic 915, </font><font style="display: inline;font-style:italic;">Development Stage Entities</font><font style="display: inline;">, from the FASB Accounting Standards Codification. ASC Topic 915 is removed effective for annual periods beginning after December 15, 2014 and early adoption is permitted. The Company adopted the ASU effective with the issuance of the June 30, 2014 interim financial statements.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In August 2014, the FASB issued ASU No. 2014-15, </font><font style="display: inline;font-style:italic;">Disclosure of Uncertainties About an Entity’s Ability to Continue as a Going Concern</font><font style="display: inline;">, which provides guidance on determining when and how to disclose going-concern uncertainties in the financial statements. The new standard requires management to perform interim and annual assessments of an entity’s ability to continue as a going concern within one year of the date the financial statements are issued. An entity must provide certain disclosures if conditions or events raise substantial doubt about the entity’s ability to continue as a going concern. The ASU applies to all entities and is effective for annual periods ending after December 15, 2016, and interim periods thereafter, with early adoption permitted. The Company is currently evaluating the impact the adoption of this ASU will have on its financial statements.</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
8634000
10037000
49720000
9251000
9251000
48960000
48960000
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Cash and Cash Equivalents</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We consider all highly liquid investments that have maturities of three months or less when acquired to be cash equivalents. As of December 31, 2014 and 2013, we invested a portion of our cash balances in money market investments, which we have included as cash equivalents on our balance sheets.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
37991
461000
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">9. Commitments and Contingencies</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Leases</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In October 2014, we entered into a five-year operating lease agreement for office space in Radnor, Pennsylvania. Rent payments under this lease commence May 1, 2015, with payment amounts escalating each May 1 thereafter through the end of the lease term. In February 2013, we entered into a two-year operating lease agreement for office space in New Haven, Connecticut and pay a flat rent per month over the term of the lease which ends in June 2015. Prior to that and through April 2013, we leased a facility in Branford, Connecticut. Rent expense under these operating leases, in thousands, was $50 and $34 for the years ended 2014 and 2013, respectively. All leases are non-cancelable.</font>
</p>
<p style="margin:0pt;text-align:center;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Our annual future minimum lease payments under these leases are as follows (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 73.00%;margin-left:72pt;">
<tr>
<td valign="bottom" style="width:78.86%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Operating </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Lease </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Payments</font></p>
</td>
<td valign="bottom" style="width:01.38%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.86%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2015 </font></p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>100
</td>
<td valign="bottom" style="width:01.38%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.86%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2016 </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>130
</td>
<td valign="bottom" style="width:01.38%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.86%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2017 </font></p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>132
</td>
<td valign="bottom" style="width:01.38%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.86%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2018 </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>135
</td>
<td valign="bottom" style="width:01.38%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.86%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2019 </font></p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>138
</td>
<td valign="bottom" style="width:01.38%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.86%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Thereafter </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>46
</td>
<td valign="bottom" style="width:01.38%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.86%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total minimum lease payments</font></p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>681
</td>
<td valign="bottom" style="width:01.38%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Employee Benefit Plan</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We maintain a Section 401(k) retirement plan for all employees. Employees can contribute up to 50% of their eligible pay, subject to maximum amounts allowed under law. We may make discretionary profit sharing contributions, which vest over a period of four years from each employee’s commencement of employment with us. We have not made any discretionary contributions.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">License Agreement</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We are obligated to pay royalties pursuant to a license agreement with Purdue as a percentage of net product sales for direct licensed products, such as ganaxolone. The obligation to pay royalties expires, on a country-by-country basis, 10 years from the first commercial sale of a licensed product in each country. The agreement also requires that we pay Purdue a percentage of the non-royalty consideration that we receive from a sublicensee and a percentage of milestone payments for indications other than seizure disorders and vascular migraine headaches not associated with mood disorders. Under the license agreement, we are committed to use commercially reasonable efforts to develop and commercialize at least one licensed product.</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
0
0
560310
0.001
0.001
100000000
100000000
494260
14036985
465029
14007754
1000
14000
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Comprehensive Loss</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Comprehensive loss is defined as the change in equity of a business enterprise during a period from transactions and other events and circumstances from non-owner sources. Comprehensive loss was equal to net loss for all periods presented.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
70340000
-30596000
-17929000
-21814000
70333000
7000
-18777860
-12220661
-18803582
7661871
2761000
2330955
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">6. Notes Payable</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In April 2014, we borrowed $2.0 million in connection with a term loan pursuant to a Loan and Security Agreement (LSA) we entered into with a financial institution. In connection with this term loan, we issued to the financial institution warrants to purchase 37,991 shares of our Series C Preferred Stock with a term of 8 years. The warrants were net exercised and converted into 220 shares of common stock in connection with the closing our initial public offering during the third quarter of 2014. Pursuant to the terms of the LSA, we made monthly interest-only payments for outstanding borrowings at an interest rate equal to the greater of (a) prime plus 2.25% or (b) 5.5% until the LSA was amended in December 2014.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In December 2014, we entered into a First Amendment to Loan and Security Agreement (Amended LSA) with the same financial institution. The Amended LSA increased the total term loan availability from $2.0 million to $12.0 million, available in four tranches (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 60.00%;margin-left:108pt;">
<tr>
<td valign="bottom" style="width:22.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Tranche</font></p>
</td>
<td valign="bottom" style="width:04.16%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Term </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Loan </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Available</font></p>
</td>
<td valign="bottom" style="width:04.16%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Term </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Loan </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Borrowed</font></p>
</td>
<td valign="bottom" style="width:04.16%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:23.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Borrowed Date</font></p>
</td>
<td valign="bottom" style="width:01.64%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:22.88%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">A</font></p>
</td>
<td valign="bottom" style="width:04.16%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:18.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,000
</td>
<td valign="bottom" style="width:04.16%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:18.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,000
</td>
<td valign="bottom" style="width:04.16%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:23.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">April 2014</font></p>
</td>
<td valign="bottom" style="width:01.64%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:22.88%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">B</font></p>
</td>
<td valign="bottom" style="width:04.16%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>5,000
</td>
<td valign="bottom" style="width:04.16%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>5,000
</td>
<td valign="bottom" style="width:04.16%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:23.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">December 2014</font></p>
</td>
<td valign="bottom" style="width:01.64%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:22.88%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">C</font></p>
</td>
<td valign="bottom" style="width:04.16%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.00%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,500
</td>
<td valign="bottom" style="width:04.16%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:04.16%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:23.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">*</font></p>
</td>
<td valign="bottom" style="width:01.64%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:22.88%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">D</font></p>
</td>
<td valign="bottom" style="width:04.16%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,500
</td>
<td valign="bottom" style="width:04.16%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:04.16%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:23.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">*</font></p>
</td>
<td valign="bottom" style="width:01.64%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:22.88%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:04.16%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:18.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>12,000
</td>
<td valign="bottom" style="width:04.16%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:18.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>7,000
</td>
<td valign="bottom" style="width:04.16%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:23.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.64%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">* Our ability to borrow under the remaining tranches of $2.5 million each depends upon meeting certain clinical trial milestones. The availability end dates of Tranches C and D are September 1, 2015 and March 31, 2016, respectively.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:42pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In connection with the Amended LSA, we borrowed $5.0 million available to us under Tranche B. Pursuant to the terms of the Amended LSA, we are required to make monthly interest-only payments for all outstanding borrowings at an interest rate equal to the greater of (a) prime plus 3.25% or (b) 6.5% until December 2015. Commencing in January 2016 and continuing through December 2017, we are required to make monthly payments of 1/24th of our principal borrowings plus interest with the remaining principal balance due in December 2017. If we achieve certain clinical trial milestones by August 2015, both the interest-only period and principal maturity dates will be extended by six months.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">As of December 31, 2014, our outstanding term loan balance of $7.0 million was classified as long-term debt on our balance sheet. In connection with the execution of both the LSA and Amended LSA, we paid debt costs to the financial institution of $25 thousand, which are being amortized into interest expense over the remaining term of the loans. Interest expense related to the loans was $117 thousand for the year ended December 31, 2014. As of December 31, 2014, we had accrued interest of $39 thousand. There are no financial covenants associated with these term loans. As of December 31, 2014, we were in compliance with all non-financial covenants.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Maturities of our debt obligations over the next five years are as follows (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 73.00%;margin-left:72pt;">
<tr>
<td valign="bottom" style="width:78.88%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Debt </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Maturities</font></p>
</td>
<td valign="bottom" style="width:01.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.88%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2015 </font></p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.88%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2016 </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3,500
</td>
<td valign="bottom" style="width:01.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.88%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2017 </font></p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3,500
</td>
<td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.88%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total minimum lease payments</font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>7,000
</td>
<td valign="bottom" style="width:01.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
0.0325
0.0225
prime
prime
0.065
0.055
2000
1000
1000
5000
25861000
29796000
23006000
26505000
59000000
68000000
2693000
3075000
143000
211000
18000
25859000
29795000
2000
1000
0.50
10000
5000
10000
5000
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">8. Stock Option and Incentive Plans</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In 2005, we adopted the 2005 Stock Option and Incentive Plan (2005 Plan) that authorizes us to grant options, restricted stock and other equity-based awards. As of December 31, 2014, 970,574 options to purchase shares of common stock were outstanding pursuant to grants in connection with the 2005 Plan. No addtional shares are available for issuance under the 2005 plan. The amount, terms of grants, and exercisability provisions are determined and set by our board of directors.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Effective in August 2014, we adopted our 2014 Equity Incentive Plan (2014 Plan) that </font><font style="display: inline;">authorizes us to grant options, restricted stock and other equity-based awards, subject to adjustment in accordance with the plan. As of December 31, 2014, 700,000 options to purchase shares of common stock were outstanding pursuant to grants in connection with the 2014 Plan; and no shares of common stock were available for future issuance. In accordance with the 2014 Plan, on January 1, 2015, 560,310 shares of common stock became available for future grant under the plan.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">There were 1,670,574 stock options outstanding as of December 31, 2014 at a weighted average exercise price of $4.37 per share, and 54,000 options were granted to nonemployee directors and consultants during the year ended December 31, 2014. Total compensation cost recognized for all stock option awards in the statements of operations is as follows (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 66.00%;margin-left:90pt;">
<tr>
<td valign="bottom" style="width:55.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.76%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="5" valign="bottom" style="width:39.76%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Year Ended</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:01.46%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:55.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.76%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:18.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.76%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:18.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.46%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:55.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Research and development </font></p>
</td>
<td valign="bottom" style="width:03.76%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:16.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>137
</td>
<td valign="bottom" style="width:03.76%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:16.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>15
</td>
<td valign="bottom" style="width:01.46%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:55.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">General and administrative </font></p>
</td>
<td valign="bottom" style="width:03.76%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:18.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>561
</td>
<td valign="bottom" style="width:03.76%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:18.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>221
</td>
<td valign="bottom" style="width:01.46%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:55.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total stock-based compensation expense </font></p>
</td>
<td valign="bottom" style="width:03.76%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:16.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>698
</td>
<td valign="bottom" style="width:03.76%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:16.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>236
</td>
<td valign="bottom" style="width:01.46%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-style:italic;">Stock Options</font>
</p>
<p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Options issued under both the 2005 Plan and 2014 Plan may have a contractual life of up to 10 years and may be exercisable in cash or as otherwise determined by the board of directors. Vesting generally occurs over a period of not greater than four years. A summary of activity for the years ended December 31, 2014 and 2013 is presented below (in thousands, except share and per share amounts):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;margin-left:18pt;">
<tr>
<td valign="bottom" style="width:52.32%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Shares</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Weighted-</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Average</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Exercise </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Price</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Per Share</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Aggregate</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Intrinsic</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Value</font></p>
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Outstanding—December 31, 2012 </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>689,663
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Granted </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>589,719
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Exercised </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(15,515
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.04
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Forfeited </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(170,659
</td>
<td valign="bottom" style="width:02.68%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Outstanding—December 31, 2013 </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,093,208
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.04
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Granted </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>700,000
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>8.99
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Exercised </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(122,634
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.04
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Outstanding—December 31, 2014 </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,670,574
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>4.37
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>10,357
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Exercisable—December 31, 2014 </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>764,338
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.75
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6,740
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Exercisable and Expected to vest—December 31, 2014 </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,670,574
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>4.37
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>10,357
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-align:center;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The weighted average remaining contractual term of options outstanding and exercisable as of December 31, 2014 is 8.6 and 7.4 years, respectively. The aggregate intrinsic value in the preceding tables represent the total intrinsic value that would have been received had all option holders exercised their options on December 31, 2014. Intrinsic value is determined by calculating the difference between the fair value of our common stock on the last day of the year and the exercise price, multiplied by the number of options.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The weighted-average grant date fair value of options granted was $6.09 and $0.85 per share in 2014 and 2013 and was estimated at the date of grant using the Black-Scholes option-pricing model with the following weighted-average assumptions:</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;margin-left:18pt;">
<tr>
<td valign="bottom" style="width:61.34%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:03.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:61.34%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Expected stock price volatility </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">77.66 — 86.08%</font></p>
</td>
<td valign="bottom" style="width:03.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">103.9 - 118.0%</font></p>
</td>
<td valign="bottom" style="width:03.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:61.34%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Expected term of options </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">5.5 — 6.06 years</font></p>
</td>
<td valign="bottom" style="width:03.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">5 - 6.25 years</font></p>
</td>
<td valign="bottom" style="width:03.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:61.34%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Risk-free interest rate </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">1.75 — 1.98%</font></p>
</td>
<td valign="bottom" style="width:03.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">0.84 - 1.75%</font></p>
</td>
<td valign="bottom" style="width:03.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:61.34%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Expected annual dividend yield </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>0%
</td>
<td valign="bottom" style="width:03.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>0%
</td>
<td valign="bottom" style="width:03.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The weighted-average valuation assumptions were determined as follows:</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 00.00pt; display: inline;">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> ·</font>
</p>
</td><td style="width:18pt;"><p style="width:18pt;width:18pt;font-size:0pt;"></p></td><td align="left" valign="top">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="display: inline;color:#000000;">Expected stock price volatility: The expected volatility is based on historical volatilities of similar entities within our industry which were commensurate with our expected term assumption as described in the SEC’s Staff Accounting Bulletin, or SAB, No. 107.</font></p></td></tr></table></div>
<p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 00.00pt; display: inline;">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> ·</font>
</p>
</td><td style="width:18pt;"><p style="width:18pt;width:18pt;font-size:0pt;"></p></td><td align="left" valign="top">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="display: inline;color:#000000;">Expected term of options: We estimated the expected term of our stock options with service-based vesting using the “simplified” method, as prescribed in SAB No. 107, whereby the expected life equals the average of the vesting tranches and the original contractual term of the option due to our lack of sufficient historical data.</font></p></td></tr></table></div>
<p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 00.00pt; display: inline;">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> ·</font>
</p>
</td><td style="width:18pt;"><p style="width:18pt;width:18pt;font-size:0pt;"></p></td><td align="left" valign="top">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="display: inline;color:#000000;">Risk-free interest rate: We base the risk-free interest rate on the interest rate payable on U.S. Treasury securities in effect at the time of grant for a period that is commensurate with the assumed expected option term.</font></p></td></tr></table></div>
<p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 00.00pt; display: inline;">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> ·</font>
</p>
</td><td style="width:18pt;"><p style="width:18pt;width:18pt;font-size:0pt;"></p></td><td align="left" valign="top">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="display: inline;color:#000000;">Expected annual dividend yield: The estimated annual dividend yield is 0% because we have not historically paid, and do not expect for the foreseeable future to pay, a dividend on our common stock.</font></p></td></tr></table></div>
<p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">As of December 31, 2014, there was $4.1 million of total unrecognized compensation expense related to unvested stock options granted under the 2005 Plan and 2014 Plan. That expense is expected to be recognized in the years ended as follows, in thousands:</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;margin-left:18pt;">
<tr>
<td valign="top" style="width:83.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">December 31, 2015 </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,448
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:83.40%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">December 31, 2016 </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,302
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:83.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">December 31, 2017 </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>929
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:83.40%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">December 31, 2018 </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>403
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:83.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>4,082
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
-3.82
-19.60
-5.66
-4.58
-5.54
-7.09
-2.17
-7.98
-0.22
-0.26
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Loss Per Share of Common Stock</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Basic loss per share is computed by dividing net loss applicable to common stockholders by the weighted average number of shares of common stock outstanding during each period. Diluted loss per share includes the effect, if any, from the potential exercise or conversion of securities, such as convertible preferred stock, convertible notes payable, warrants, stock options, and unvested restricted stock, which would result in the issuance of incremental shares of common stock. In computing the basic and diluted net loss per share applicable to common stockholders, the weighted average number of shares remains the same for both calculations due to the fact that when a net loss exists, dilutive shares are not included in the calculation. These potentially dilutive securities are more fully described in Note 7.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The following table sets forth the computation of basic and diluted earnings per share for the years ended December 31, 2014 and 2013 (in thousands, except share and per share amounts):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 73.00%;margin-left:72pt;">
<tr>
<td valign="bottom" style="width:59.10%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="5" valign="bottom" style="width:36.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Year Ended December 31,</font></p>
</td>
<td valign="bottom" style="width:01.38%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:59.10%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.38%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.10%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Basic and diluted net loss per share of common stock:</font></p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.38%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.10%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(10,833
</td>
<td valign="bottom" style="width:03.40%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5,270
</td>
<td valign="bottom" style="width:01.38%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.10%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Dividends on Series B and C Preferred Stock </font></p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,545
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,804
</td>
<td valign="bottom" style="width:01.38%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.10%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss applicable to common stockholders </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(13,378
</td>
<td valign="bottom" style="width:03.40%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(9,074
</td>
<td valign="bottom" style="width:01.38%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.10%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Weighted average shares of common stock outstanding </font></p>
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6,152,669
</td>
<td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.36%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>462,972
</td>
<td valign="bottom" style="width:01.38%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.10%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss per share of common stock—basic and diluted </font></p>
</td>
<td valign="bottom" style="width:03.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2.17
</td>
<td valign="bottom" style="width:03.40%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.06%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(19.60
</td>
<td valign="bottom" style="width:01.38%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The following potentially dilutive securities outstanding at December 31, 2014 and 2013 have been excluded from the computation of diluted weighted average shares outstanding, as they would be antidilutive:</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 80.00%;margin-left:54pt;">
<tr>
<td valign="bottom" style="width:62.48%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="3" valign="bottom" style="width:33.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:62.48%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Convertible preferred stock </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>7,596,927
</td>
<td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Warrants </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>470,026
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Stock options </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,670,574
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,093,208
</td>
<td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,670,574
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>9,160,161
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
0.007
0.000
0.340
0.340
-0.354
-0.366
-0.003
-0.054
0.050
0.038
-0.033
0.042
204000
419000
4082000
403000
1448000
929000
1302000
-153000
-1192000
P4Y
P2M12D
0.80
0.75
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">3. Fair Value Measurements</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">FASB accounting guidance defines fair value as the price that would be received to sell an asset or paid to transfer a liability (the exit price) in an orderly transaction between market participants at the measurement date. The accounting guidance outlines a valuation framework and creates a fair value hierarchy in order to increase the consistency and comparability of fair value measurements and the related disclosures. In determining fair value, we use quoted prices and observable inputs. Observable inputs are inputs that market participants would use in pricing the asset or liability based on market data obtained from independent sources.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The fair value hierarchy is broken down into three levels based on the source of inputs as follows:</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 00.00pt; display: inline;">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> ·</font>
</p>
</td><td style="width:18pt;"><p style="width:18pt;width:18pt;font-size:0pt;"></p></td><td align="left" valign="top">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="display: inline;color:#000000;">Level 1—Valuations based on unadjusted quoted prices in active markets for identical assets or liabilities.</font></p></td></tr></table></div>
<p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 00.00pt; display: inline;">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> ·</font>
</p>
</td><td style="width:18pt;"><p style="width:18pt;width:18pt;font-size:0pt;"></p></td><td align="left" valign="top">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="display: inline;color:#000000;">Level 2—Valuations based on observable inputs and quoted prices in active markets for similar assets and liabilities.</font></p></td></tr></table></div>
<p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 00.00pt; display: inline;">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> ·</font>
</p>
</td><td style="width:18pt;"><p style="width:18pt;width:18pt;font-size:0pt;"></p></td><td align="left" valign="top">
<p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;">
<font style="display: inline;color:#000000;">Level 3—Valuations based on inputs that are unobservable and models that are significant to the overall fair value measurement.</font></p></td></tr></table></div>
<p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">The following fair value hierarchy table presents information about each major category of our financial assets and liabilities measured at fair value on a recurring basis (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:41.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;"> </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;">Level 1</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;">Level 2</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;">Level 3</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;">Total</font></p>
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;color:#000000;">December 31, 2014</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;color:#000000;">Assets</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">Money market funds (cash equivalents) </font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>48,960
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>48,960
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">Total assets </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>48,960
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>48,960
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;color:#000000;">December 31, 2013</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;color:#000000;">Assets</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">Money market funds (cash equivalents) </font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>9,251
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>9,251
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">Total assets </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>9,251
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>9,251
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;color:#000000;">Liabilities</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">Warrant liability </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,192
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,192
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">Total liabilities </font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,192
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,192
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">We had outstanding warrants to purchase our Series B Preferred Stock, or the Series B Warrants, as of December 31, 2013. While the Series B Preferred Stock was outstanding, holders were able to redeem for cash upon an event that was not within our control, such as the liquidation of our preferred stock, as the preferred stockholders had voting control of our company and control of our board of directors, and therefore had the ability to trigger the liquidation of our preferred stock. As a result, the Series B Warrants were recorded as a warrant liability on our balance sheet with subsequent changes to fair value recorded on our statements of operations as change in fair value of warrant liability. In connection with our initial public offering during the third quarter of 2014, these warrants expired unexercised, and the Series B Preferred Stock underlying the Series B Warrants converted to common stock. </font><font style="display: inline;color:#000000;">As a result, the fair value of the Series B warrants recorded as a liability as of December 31, 2013 was reduced to zero in 2014.</font><font style="display: inline;color:#000000;"> On the grant date and in subsequent periods, we estimated the fair value of the preferred stock warrant liability using an option-pricing model, which required inputs such as the expected volatility based on comparable public companies (75% - 80%), the estimated fair value of the Series B Preferred Stock ($0.63 - $1.51 per share), and the estimated time to liquidity (0.2 - 4 years). For this liability, we developed our own assumptions that do not have observable inputs or available market data to support the fair value.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">The following tables set forth a summary of changes in the fair value of Level 3 preferred stock warrant liability for the years ended December 31, 2014 and 2013 (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:34.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;"> </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;">Beginning </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;">of</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;">Year</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;">Issuances</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;">Exercises</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;">Change in Fair</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;">Value</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;color:#000000;">End of Year</font></p>
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:34.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">Year ended December 31, 2014 </font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,192
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,192
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:34.50%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">Year ended December 31, 2013 </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,345
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(153
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,192
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;color:#000000;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The following tables set forth a summary of changes in the fair value of Level 3 preferred stock warrant liability for the years ended December 31, 2014 and 2013 (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:34.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Beginning </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">of</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Year</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Issuances</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Exercises</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Change in Fair</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Value</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">End of Year</font></p>
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:34.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Year ended December 31, 2014 </font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,192
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,192
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:34.50%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Year ended December 31, 2013 </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,345
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(153
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,192
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
-153000
-1192000
1345000
1192000
180000
1229000
314000
313000
422000
517000
3230000
458000
868000
1387000
0
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Impairment of Long-Lived Assets</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We review long-lived assets, including property and equipment, for impairment whenever events or changes in business circumstances indicate that the carrying amount of an asset may not be fully recoverable. If the estimated undiscounted future cash flows expected to result from the use of the asset and its eventual disposition is less than its carrying amount an impairment loss would be recognized if the carrying value of the asset exceeded its fair value. Fair value is generally determined using discounted cash flows. Through December 31, 2014, no impairment has occurred.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">10. Income Taxes</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">As of December 31, 2014 and 2013, we had approximately $68.0 million and $59.0 million, respectively, of net operating loss, or NOL, carry forwards available to offset future federal and state taxable income that will expire beginning in 2023. We also have federal research and development credit carryovers of approximately $2.6 million and state credit carryovers of approximately $0.4 million which expire beginning in 2019.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The State of Connecticut provides companies with the opportunity to exchange certain research and development credit carryforwards for cash in exchange for foregoing the carryforward. The program provides for such exchange of the research and development credits at a rate of 65% of the annual research and development credit, as defined. During 2014 and 2013, we recorded a net benefit, in thousands, of $2 and $28, respectively, primarily for the estimated proceeds from the exchange of the research and development credit.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The NOL carry forwards are subject to review and possible adjustment by the Internal Revenue Service and state tax authorities. NOL, and tax credit carry forwards may become subject to an annual limitation in the event of certain cumulative changes in the ownership interest of significant stockholders over a three-year period in excess of 50%, as defined under Sections 382 and 383 of the Internal Revenue Code of 1986, as amended, or the Code, as well as similar state tax provisions. This could limit the amount of NOLs that we can utilize annually to offset future taxable income or tax liabilities. The amount of the annual limitation, if any, will be determined based on the value of our company immediately prior to an ownership change. Subsequent ownership changes may further affect the limitation in future years. Additionally, U.S. tax laws limit the time during which these carry forwards may be applied against future taxes, therefore, we may not be able to take full advantage of these carry forwards for federal income tax purposes. We are currently evaluating the ownership history of our company to determine if there were any ownership changes as defined under Section 382(g) of the Code and the effects any ownership change may have had.</font>
</p>
<p style="margin:0pt;text-align:center;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The components of the net deferred tax asset are as follows (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;margin-left:18pt;">
<tr>
<td valign="bottom" style="width:67.90%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="5" valign="bottom" style="width:28.22%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:01.20%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:67.90%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.20%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Gross deferred tax assets:</font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net operating loss carryovers </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>26,505
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.38%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>23,006
</td>
<td valign="bottom" style="width:01.20%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Accrued expenses </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>18
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Contributions </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>5
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1
</td>
<td valign="bottom" style="width:01.20%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Stock-based compensation </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>211
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>143
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Research and development and other credits </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3,075
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,693
</td>
<td valign="bottom" style="width:01.20%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total gross deferred tax assets </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>29,796
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>25,861
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Gross deferred tax liabilities:</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.20%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Depreciation </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total gross deferred tax liabilities </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1
</td>
<td valign="bottom" style="width:02.68%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2
</td>
<td valign="bottom" style="width:01.20%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net deferred tax assets </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>29,795
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>25,859
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Less: valuation allowance </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(29,795
</td>
<td valign="bottom" style="width:02.68%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(25,859
</td>
<td valign="bottom" style="width:01.20%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net deferred tax assets after valuation allowance </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.38%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In assessing the realizability of deferred tax assets, we consider whether it is more-likely-than-not that some portion or all of the deferred tax assets will not be realized. The ultimate realization of deferred tax assets is dependent upon the generation of future taxable income during the periods in which the temporary differences representing net future deductible amounts become deductible. After consideration of all the evidence, both positive and negative, we have recorded a full valuation allowance against our net deferred tax assets at December 31, 2014 and 2013, respectively, because our management has determined that is it more likely than not that these assets will not be fully realized. The valuation allowance increased by $3.9 million and $2.3 million during the years ended December 31, 2014 and 2013, respectively, due primarily to the generation of NOLs during those periods.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We did not have unrecognized tax benefits as of December 31, 2014 and 2013, and do not expect this to change significantly over the next twelve months. We recognize interest and penalties accrued on any unrecognized tax benefits as a component of income tax expense. As of December 31, 2014 and 2013, we have not accrued interest or penalties related to any uncertain tax positions. Our tax returns filed since inception are still subject to examination by major tax jurisdictions.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">A reconciliation of income tax expense (benefit) at the statutory federal income tax rate and income taxes as reflected in the financial statements is as follows:</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;margin-left:18pt;">
<tr>
<td valign="bottom" style="width:67.90%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="3" valign="bottom" style="width:27.02%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Year Ended</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:02.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:67.90%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:11.48%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:02.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Federal income tax expense at statutory rate </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>34.0
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">%</font></p>
</td>
<td valign="bottom" style="width:11.48%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>34.0
</td>
<td valign="bottom" style="width:02.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">%</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Permanent items </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5.4
</td>
<td valign="bottom" style="width:02.68%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:11.48%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(0.3
</td>
<td valign="bottom" style="width:02.40%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">State income tax, net of federal benefit </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3.8
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:11.48%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>5.0
</td>
<td valign="bottom" style="width:02.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">State refundable credit </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>0.0
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:11.48%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>0.7
</td>
<td valign="bottom" style="width:02.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">R&D tax credits </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>4.2
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:11.48%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3.3
</td>
<td valign="bottom" style="width:02.40%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Change in valuation allowance </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(36.6
</td>
<td valign="bottom" style="width:02.68%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:11.48%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(35.4
</td>
<td valign="bottom" style="width:02.40%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Effective income tax rate </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>0.0
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">%</font></p>
</td>
<td valign="bottom" style="width:11.48%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>0.7
</td>
<td valign="bottom" style="width:02.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">%</font></p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">For all years through December 31, 2014, we generated research credits but have not conducted a study to document the qualified activities. This study may result in an adjustment to our research and development credit carryforwards; however, until a study is completed and any adjustment is known, no amounts are being presented as an uncertain tax position for these years. A full valuation allowance has been provided against our research and development credits and, if an adjustment is required, this adjustment to the deferred tax asset established for the research and development credit carryforwards would be offset by an adjustment to the valuation allowance.</font>
</p>
<p style="margin:0pt;text-align:center;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We file income tax returns in the United States, the State of Connecticut, and the Commonwealth of Pennsylvania. The federal and state income tax returns are generally subject to tax examinations for the tax years ended December 31, 2011 through December 31, 2013. To the extent we have tax attribute carryforwards, the tax years in which the attribute was generated may still be adjusted upon examination by the Internal Revenue Service or state tax authorities to the extent utilized in a future period.</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Income Taxes</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We recognize deferred tax assets and liabilities for temporary differences between the financial reporting basis and the tax basis of our assets and liabilities and the expected benefits of net operating loss carryforwards. The impact of changes in tax rates and laws on deferred taxes, if any, applied during the years in which temporary differences are expected to be settled, is reflected in the financial statements in the period of enactment. The measurement of deferred tax assets is reduced, if necessary, if, based on weight of the evidence, it is more likely than not that some, or all, of the deferred tax assets will not be realized. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in the period that such tax rate changes are enacted. At December 31, 2014 and 2013, we have concluded that a full valuation allowance is necessary for our net deferred tax assets. We had no material amounts recorded for uncertain tax positions, interest or penalties in the accompanying consolidated financial statements.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
189000
1385000
1731000
-1344000
91000
117000
117000
47000
12000
89000
39000
P2Y
P5Y
2366000
9059000
11824000
50213000
2366000
2039000
1192000
1192000
5000000
2000000
7000000
5000000
2500000
2500000
2000000
12000000
25000
7000000
3500000
3500000
7000000
1403000
39683000
8048000
48305000
-17000
-33000
-6628000
-8589000
-970000
-5270000
-5270000
-1682000
-1224000
-1394000
-2235000
-10833000
-10833000
-3323000
-1668000
-3607000
-1756000
-9074000
-2622000
-2253000
-2443000
-3306000
-13378000
-4425000
-2040000
-3607000
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Recent Accounting Pronouncements</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In June 2014, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update (ASU) No. 2014-10, </font><font style="display: inline;font-style:italic;">Elimination of Certain Financial Reporting Requirements, Including an Amendment to Variable Interest Entities Guidance in Topic 810, Consolidation</font><font style="display: inline;">, which eliminates all incremental financial reporting requirements for development stage entities by removing Accounting Standards Codification (ASC) Topic 915, </font><font style="display: inline;font-style:italic;">Development Stage Entities</font><font style="display: inline;">, from the FASB Accounting Standards Codification. ASC Topic 915 is removed effective for annual periods beginning after December 15, 2014 and early adoption is permitted. The Company adopted the ASU effective with the issuance of the June 30, 2014 interim financial statements.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In August 2014, the FASB issued ASU No. 2014-15, </font><font style="display: inline;font-style:italic;">Disclosure of Uncertainties About an Entity’s Ability to Continue as a Going Concern</font><font style="display: inline;">, which provides guidance on determining when and how to disclose going-concern uncertainties in the financial statements. The new standard requires management to perform interim and annual assessments of an entity’s ability to continue as a going concern within one year of the date the financial statements are issued. An entity must provide certain disclosures if conditions or events raise substantial doubt about the entity’s ability to continue as a going concern. The ASU applies to all entities and is effective for annual periods ending after December 15, 2016, and interim periods thereafter, with early adoption permitted. The Company is currently evaluating the impact the adoption of this ASU will have on its financial statements.</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
1
-5379000
-11920000
681000
100000
138000
135000
132000
130000
46000
34000
50000
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">1. Organization and Description of the Business</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We are a biopharmaceutical company dedicated to the development of innovative neuropsychiatric therapeutics. Our clinical stage product candidate, ganaxolone, is a synthetic small molecule that is an analog of allopregnanolone, a natural occurring neurosteriod produced by the human body. Allopregnanolone modulates the activity of gammaaminobutyric acid (GABA) at GABA</font><font style="display: inline;font-size:6.5pt;">A</font><font style="display: inline;"> type receptors in the brain, which has been identified as playing an important role in certain seizure, psychiatric and developmental disorders. Our primary focus to date since our inception has been directed towards developing business strategies, raising capital, research and development activities and conducting preclinical testing and human clinical trials of our product candidates.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Liquidity</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We have not generated any product revenues and have incurred operating losses since inception. There is no assurance that profitable operations will ever be achieved, and if achieved, could be sustained on a continuing basis. In addition, development activities, clinical and preclinical testing, and commercialization of our product candidates will require significant additional financing. Our accumulated deficit as of December 31, 2014 was $72.3 million and we expect to incur substantial losses in future periods. We plan to finance our future operations with a combination of proceeds from the issuance of equity securities, the issuance of additional debt, potential collaborations and revenues from potential future product sales, if any. We have not generated positive cash flows from operations, and there are no assurances that we will be successful in obtaining an adequate level of financing for the development and commercialization of our planned product candidates.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">In connection with the closing our initial public offering during the third quarter of 2014, we issued a total of 5,758,000 shares of common stock and received aggregate net proceeds, after underwriting discounts and commissions and other estimated offering expenses, of approximately $41.2 million. Our cash and cash equivalents balance as of December 31, 2014 is adequate to fund our operations into the second half of 2016.</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
24000
121000
20000
9000
21000
91000
17000
33000
786000
3804000
940000
1029000
1049000
1071000
2545000
1102000
372000
0.001
0.001
25000000
25000000
0
0
0
0
1762000
428000
41202000
41200000
7500000
500000
7530000
2000000
6975000
18000
128000
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">4. Property and Equipment</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Property and equipment consisted of the following (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 80.00%;margin-left:54pt;">
<tr>
<td valign="bottom" style="width:62.48%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="5" valign="bottom" style="width:33.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:62.48%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Laboratory equipment </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>326
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>369
</td>
<td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Office equipment </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>74
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>76
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>400
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>445
</td>
<td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Less: accumulated depreciation</font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(356
</td>
<td valign="bottom" style="width:03.12%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(429
</td>
<td valign="bottom" style="width:01.26%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.48%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>44
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>16
</td>
<td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Depreciation expense, in thousands, was $5 and $10 for the years ended December 31, 2014 and 2013, respectively.</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
445000
369000
76000
400000
326000
74000
16000
44000
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Property and Equipment</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Property and equipment consist of laboratory and office equipment and are recorded at cost. Property and equipment are depreciated on a straight-line basis over their estimated useful lives. We estimate a life of three years for computer equipment, including software, and five years for laboratory equipment, office equipment, and furniture. When property and equipment are sold or otherwise disposed of, the cost and related accumulated depreciation are removed from the accounts and the resulting gain or loss is included in operating expenses.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Property and equipment consisted of the following (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:62.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="5" valign="bottom" style="width:33.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:62.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Laboratory equipment </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>326
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>369
</td>
<td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.50%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Office equipment </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>74
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>76
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>400
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>445
</td>
<td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.50%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Less: accumulated depreciation</font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(356
</td>
<td valign="bottom" style="width:03.12%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(429
</td>
<td valign="bottom" style="width:01.26%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>44
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>16
</td>
<td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
P3Y
P5Y
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">11. Quarterly Financial Information (unaudited)</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:36.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">First </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Quarter</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Second </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Quarter</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Third </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Quarter</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Fourth </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Quarter</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Total Year</font></p>
</td>
<td valign="bottom" style="width:01.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">2014:</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Research and development expenses</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,149
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,805
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,569
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,167
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>8,690
</td>
<td valign="bottom" style="width:01.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">General and administrative expenses</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>517
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>458
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>868
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,387
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3,230
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,235
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,323
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,668
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,607
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(10,833
</td>
<td valign="bottom" style="width:01.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Cumulative preferred stock dividends</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,071
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,102
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(372
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,543
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss applicable to common shareholders</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,306
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(4,425
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,040
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,607
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(13,378
</td>
<td valign="bottom" style="width:01.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss per share, basic and diluted</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(7.09
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(7.98
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(0.22
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(0.26
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2.17
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">2013:</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Research and development expenses</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>747
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,327
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,008
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,068
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>4,150
</td>
<td valign="bottom" style="width:01.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">General and administrative expenses</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>180
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>314
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>313
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>422
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,229
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(970
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,682
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,224
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,394
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5,270
</td>
<td valign="bottom" style="width:01.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Cumulative preferred stock dividends</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(786
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(940
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,029
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,049
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,804
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss applicable to common shareholders</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,756
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,622
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,253
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,443
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(9,074
</td>
<td valign="bottom" style="width:01.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss per share, basic and diluted</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3.82
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5.66
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(4.58
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5.54
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(19.60
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
747000
4150000
1327000
1008000
1068000
2149000
8690000
2805000
1569000
2167000
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Research and Development</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Research and development costs are expensed as incurred. Costs for certain development activities, such as clinical trials, are recognized based on an evaluation of the progress to completion of specific tasks using data such as subject enrollment, clinical site activations, or information provided to us by our vendors with respect to their actual costs incurred. Payments for these activities are based on the terms of the individual arrangements, which may differ from the pattern of costs incurred, and are reflected in the financial statements as prepaid or accrued research and development expense, as the case may be.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
-61503000
-72336000
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">At December 31, 2014 and 2013, accrued expenses consisted of the following (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:62.52%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="5" valign="bottom" style="width:33.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:01.24%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:62.52%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.24%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.52%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Investor deposit </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>500
</td>
<td valign="bottom" style="width:01.24%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.52%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Payroll and related costs </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>419
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>204
</td>
<td valign="bottom" style="width:01.24%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.52%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Clinical trials and drug development </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>777
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>73
</td>
<td valign="bottom" style="width:01.24%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.52%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Professional fees </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>186
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>295
</td>
<td valign="bottom" style="width:01.24%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.52%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Other </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>121
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>24
</td>
<td valign="bottom" style="width:01.24%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:62.52%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,503
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:13.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,096
</td>
<td valign="bottom" style="width:01.24%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;"></font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:62.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="3" valign="bottom" style="width:33.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:62.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Convertible preferred stock </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>7,596,927
</td>
<td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.50%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Warrants </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>470,026
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Stock options </font></p>
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,670,574
</td>
<td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,093,208
</td>
<td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:62.50%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,670,574
</td>
<td valign="bottom" style="width:03.12%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>9,160,161
</td>
<td valign="bottom" style="width:01.26%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The components of the net deferred tax asset are as follows (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;margin-left:18pt;">
<tr>
<td valign="bottom" style="width:67.90%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="5" valign="bottom" style="width:28.22%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:01.20%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:67.90%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.20%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Gross deferred tax assets:</font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net operating loss carryovers </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>26,505
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.38%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>23,006
</td>
<td valign="bottom" style="width:01.20%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Accrued expenses </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>18
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Contributions </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>5
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1
</td>
<td valign="bottom" style="width:01.20%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Stock-based compensation </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>211
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>143
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Research and development and other credits </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3,075
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,693
</td>
<td valign="bottom" style="width:01.20%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total gross deferred tax assets </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>29,796
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>25,861
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Gross deferred tax liabilities:</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.20%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Depreciation </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total gross deferred tax liabilities </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1
</td>
<td valign="bottom" style="width:02.68%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2
</td>
<td valign="bottom" style="width:01.20%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net deferred tax assets </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>29,795
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>25,859
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Less: valuation allowance </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(29,795
</td>
<td valign="bottom" style="width:02.68%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:12.68%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(25,859
</td>
<td valign="bottom" style="width:01.20%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net deferred tax assets after valuation allowance </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.38%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:01.20%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The following table sets forth the computation of basic and diluted earnings per share for the years ended December 31, 2014 and 2013 (in thousands, except share and per share amounts):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:59.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="5" valign="bottom" style="width:36.24%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Year Ended December 31,</font></p>
</td>
<td valign="bottom" style="width:01.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:59.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.44%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.44%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Basic and diluted net loss per share of common stock:</font></p>
</td>
<td valign="bottom" style="width:03.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.44%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:03.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.44%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.06%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss </font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.42%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.02%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(10,833
</td>
<td valign="bottom" style="width:03.36%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.02%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5,270
</td>
<td valign="bottom" style="width:01.36%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Dividends on Series B and C Preferred Stock </font></p>
</td>
<td valign="bottom" style="width:03.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.44%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,545
</td>
<td valign="bottom" style="width:03.36%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:16.44%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,804
</td>
<td valign="bottom" style="width:01.36%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.06%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss applicable to common stockholders </font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.42%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.02%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(13,378
</td>
<td valign="bottom" style="width:03.36%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.40%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.02%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(9,074
</td>
<td valign="bottom" style="width:01.36%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Weighted average shares of common stock outstanding </font></p>
</td>
<td valign="bottom" style="width:03.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.44%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6,152,669
</td>
<td valign="bottom" style="width:03.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.44%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>462,972
</td>
<td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:59.06%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss per share of common stock—basic and diluted </font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.42%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.02%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2.17
</td>
<td valign="bottom" style="width:03.36%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.40%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.02%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(19.60
</td>
<td valign="bottom" style="width:01.36%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;"></font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:67.90%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="3" valign="bottom" style="width:27.02%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Year Ended</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:02.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:67.90%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:11.48%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:02.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Federal income tax expense at statutory rate </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>34.0
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">%</font></p>
</td>
<td valign="bottom" style="width:11.48%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>34.0
</td>
<td valign="bottom" style="width:02.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">%</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Permanent items </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5.4
</td>
<td valign="bottom" style="width:02.68%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:11.48%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(0.3
</td>
<td valign="bottom" style="width:02.40%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">State income tax, net of federal benefit </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3.8
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:11.48%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>5.0
</td>
<td valign="bottom" style="width:02.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">State refundable credit </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>0.0
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:11.48%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>0.7
</td>
<td valign="bottom" style="width:02.40%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">R&D tax credits </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>4.2
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:11.48%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3.3
</td>
<td valign="bottom" style="width:02.40%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Change in valuation allowance </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(36.6
</td>
<td valign="bottom" style="width:02.68%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:11.48%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(35.4
</td>
<td valign="bottom" style="width:02.40%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:67.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Effective income tax rate </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>0.0
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">%</font></p>
</td>
<td valign="bottom" style="width:11.48%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>0.7
</td>
<td valign="bottom" style="width:02.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">%</font></p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total compensation cost recognized for all stock option awards in the statements of operations is as follows (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:54.94%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.66%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="5" valign="bottom" style="width:40.02%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Year Ended</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">December 31,</font></p>
</td>
<td valign="bottom" style="width:01.38%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:54.94%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.66%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:18.18%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.66%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:18.18%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:01.38%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:54.94%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Research and development </font></p>
</td>
<td valign="bottom" style="width:03.66%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.58%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:16.60%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>137
</td>
<td valign="bottom" style="width:03.66%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.56%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:16.62%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>15
</td>
<td valign="bottom" style="width:01.38%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:54.94%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">General and administrative </font></p>
</td>
<td valign="bottom" style="width:03.66%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:18.18%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>561
</td>
<td valign="bottom" style="width:03.66%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:18.18%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>221
</td>
<td valign="bottom" style="width:01.38%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:54.94%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total stock-based compensation expense </font></p>
</td>
<td valign="bottom" style="width:03.66%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.58%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:16.60%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>698
</td>
<td valign="bottom" style="width:03.66%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.56%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:16.62%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>236
</td>
<td valign="bottom" style="width:01.38%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The following fair value hierarchy table presents information about each major category of our financial assets and liabilities measured at fair value on a recurring basis (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:41.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Level 1</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Level 2</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Level 3</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Total</font></p>
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">December 31, 2014</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Assets</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Money market funds (cash equivalents) </font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>48,960
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>48,960
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total assets </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>48,960
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>48,960
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">December 31, 2013</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Assets</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Money market funds (cash equivalents) </font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>9,251
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>9,251
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total assets </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>9,251
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>9,251
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Liabilities</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.00%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Warrant liability </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,192
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,192
</td>
<td valign="bottom" style="width:01.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:41.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total liabilities </font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,192
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:10.70%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,192
</td>
<td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Our annual future minimum lease payments under these leases are as follows (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:78.82%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.46%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Operating </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Lease </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Payments</font></p>
</td>
<td valign="bottom" style="width:01.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.82%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2015 </font></p>
</td>
<td valign="bottom" style="width:03.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.42%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.04%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>100
</td>
<td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.82%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2016 </font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.46%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>130
</td>
<td valign="bottom" style="width:01.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.82%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2017 </font></p>
</td>
<td valign="bottom" style="width:03.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.46%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>132
</td>
<td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.82%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2018 </font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.46%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>135
</td>
<td valign="bottom" style="width:01.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.82%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2019 </font></p>
</td>
<td valign="bottom" style="width:03.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.46%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>138
</td>
<td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.82%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Thereafter </font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.46%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>46
</td>
<td valign="bottom" style="width:01.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.82%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total minimum lease payments</font></p>
</td>
<td valign="bottom" style="width:03.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.42%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.04%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>681
</td>
<td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The Amended LSA increased the total term loan availability from $2.0 million to $12.0 million, available in four tranches (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:22.76%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Tranche</font></p>
</td>
<td valign="bottom" style="width:04.04%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Term </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Loan </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Available</font></p>
</td>
<td valign="bottom" style="width:04.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.34%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Term </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Loan </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Borrowed</font></p>
</td>
<td valign="bottom" style="width:04.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:22.90%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Borrowed Date</font></p>
</td>
<td valign="bottom" style="width:01.54%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:22.76%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">A</font></p>
</td>
<td valign="bottom" style="width:04.04%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.72%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:18.58%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,000
</td>
<td valign="bottom" style="width:04.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.74%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:18.60%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,000
</td>
<td valign="bottom" style="width:04.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:22.90%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">April 2014</font></p>
</td>
<td valign="bottom" style="width:01.54%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:22.76%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">B</font></p>
</td>
<td valign="bottom" style="width:04.04%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.30%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>5,000
</td>
<td valign="bottom" style="width:04.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.34%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>5,000
</td>
<td valign="bottom" style="width:04.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:22.90%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">December 2014</font></p>
</td>
<td valign="bottom" style="width:01.54%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:22.76%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">C</font></p>
</td>
<td valign="bottom" style="width:04.04%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.30%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,500
</td>
<td valign="bottom" style="width:04.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.34%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:04.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:22.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">*</font></p>
</td>
<td valign="bottom" style="width:01.54%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:22.76%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">D</font></p>
</td>
<td valign="bottom" style="width:04.04%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,500
</td>
<td valign="bottom" style="width:04.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:20.34%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:04.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:22.90%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">*</font></p>
</td>
<td valign="bottom" style="width:01.54%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:22.76%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:04.04%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.72%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:18.58%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>12,000
</td>
<td valign="bottom" style="width:04.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.74%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:18.60%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>7,000
</td>
<td valign="bottom" style="width:04.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:22.90%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.54%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">* Our ability to borrow under the remaining tranches of $2.5 million each depends upon meeting certain clinical trial milestones. The availability end dates of Tranches C and D are September 1, 2015 and March 31, 2016, respectively.</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Maturities of our debt obligations over the next five years are as follows (in thousands):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:78.84%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.46%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Debt </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Maturities</font></p>
</td>
<td valign="bottom" style="width:01.34%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.84%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2015 </font></p>
</td>
<td valign="bottom" style="width:03.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.42%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.04%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:01.34%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.84%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2016 </font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.46%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3,500
</td>
<td valign="bottom" style="width:01.34%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.84%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">2017 </font></p>
</td>
<td valign="bottom" style="width:03.36%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:16.46%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3,500
</td>
<td valign="bottom" style="width:01.34%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:78.84%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Total minimum lease payments</font></p>
</td>
<td valign="bottom" style="width:03.36%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.42%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:15.04%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>7,000
</td>
<td valign="bottom" style="width:01.34%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;"></font><font style="display: inline;"></font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:36.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">First </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Quarter</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Second </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Quarter</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Third </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Quarter</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Fourth </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Quarter</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Total Year</font></p>
</td>
<td valign="bottom" style="width:01.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">2014:</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Research and development expenses</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,149
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,805
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,569
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,167
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>8,690
</td>
<td valign="bottom" style="width:01.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">General and administrative expenses</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>517
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>458
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>868
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,387
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3,230
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,235
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,323
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,668
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,607
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(10,833
</td>
<td valign="bottom" style="width:01.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Cumulative preferred stock dividends</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,071
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,102
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(372
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,543
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss applicable to common shareholders</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,306
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(4,425
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,040
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,607
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(13,378
</td>
<td valign="bottom" style="width:01.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss per share, basic and diluted</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(7.09
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(7.98
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(0.22
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(0.26
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2.17
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">2013:</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:10.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Research and development expenses</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>747
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,327
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,008
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,068
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>4,150
</td>
<td valign="bottom" style="width:01.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">General and administrative expenses</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>180
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>314
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>313
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>422
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,229
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(970
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,682
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,224
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,394
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5,270
</td>
<td valign="bottom" style="width:01.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Cumulative preferred stock dividends</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(786
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(940
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,029
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,049
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3,804
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss applicable to common shareholders</font></p>
</td>
<td valign="bottom" style="width:02.50%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(1,756
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,622
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,253
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(2,443
</td>
<td valign="bottom" style="width:02.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(9,074
</td>
<td valign="bottom" style="width:01.50%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
<tr>
<td valign="top" style="width:36.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Net loss per share, basic and diluted</font></p>
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(3.82
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5.66
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(4.58
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5.54
</td>
<td valign="bottom" style="width:02.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:08.70%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(19.60
</td>
<td valign="bottom" style="width:01.50%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">A summary of activity for the years ended December 31, 2014 and 2013 is presented below (in thousands, except share and per share amounts):</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:52.32%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Shares</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Weighted-</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Average</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Exercise </font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Price</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Per Share</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">Aggregate</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Intrinsic</font><br /><font style="display: inline;font-weight:bold;font-size:8pt;">Value</font></p>
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Outstanding—December 31, 2012 </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>689,663
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Granted </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>589,719
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Exercised </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(15,515
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.04
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Forfeited </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(170,659
</td>
<td valign="bottom" style="width:02.68%;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">—</font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Outstanding—December 31, 2013 </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,093,208
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.04
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Granted </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>700,000
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>8.99
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 20pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Exercised </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(122,634
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">)</font></p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.04
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Outstanding—December 31, 2014 </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,670,574
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>4.37
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>10,357
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Exercisable—December 31, 2014 </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>764,338
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.75
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6,740
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:52.32%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Exercisable and Expected to vest—December 31, 2014 </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:12.86%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,670,574
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>4.37
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:2pt double #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>10,357
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-align:center;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="bottom" style="width:61.34%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2014</font></p>
</td>
<td valign="bottom" style="width:03.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt">
<font style="display: inline;font-weight:bold;font-size:8pt;">2013</font></p>
</td>
<td valign="bottom" style="width:02.98%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:61.34%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Expected stock price volatility </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">77.66 — 86.08%</font></p>
</td>
<td valign="bottom" style="width:03.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">103.9 - 118.0%</font></p>
</td>
<td valign="bottom" style="width:02.98%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:61.34%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Expected term of options </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">5.5 — 6.06 years</font></p>
</td>
<td valign="bottom" style="width:03.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">5 - 6.25 years</font></p>
</td>
<td valign="bottom" style="width:02.98%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:61.34%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Risk-free interest rate </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">1.75 — 1.98%</font></p>
</td>
<td valign="bottom" style="width:03.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">0.84 - 1.75%</font></p>
</td>
<td valign="bottom" style="width:02.98%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:61.34%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Expected annual dividend yield </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>0%
</td>
<td valign="bottom" style="width:03.00%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:15.00%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>0%
</td>
<td valign="bottom" style="width:02.98%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">As of December 31, 2014, there was $4.1 million of total unrecognized compensation expense related to unvested stock options granted under the 2005 Plan and 2014 Plan. That expense is expected to be recognized in the years ended as follows, in thousands:</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<div style="width:100%"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;">
<tr>
<td valign="top" style="width:83.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">December 31, 2015 </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,448
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:83.40%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">December 31, 2016 </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,302
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:83.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">December 31, 2017 </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>929
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="top" style="width:83.40%;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">December 31, 2018 </font></p>
</td>
<td valign="bottom" style="width:02.68%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td colspan="2" valign="bottom" style="width:12.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>403
</td>
<td valign="bottom" style="width:01.06%;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="width:83.40%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt 0pt 0pt 10pt;line-height:106.67%;text-indent: -10pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font></p>
</td>
<td valign="bottom" style="width:02.68%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
<td valign="bottom" style="width:01.30%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">$</font></p>
</td>
<td valign="bottom" style="width:11.56%;border-top:1pt solid #000000 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>4,082
</td>
<td valign="bottom" style="width:01.06%;background-color: #CCEEFF;padding:0pt;">
<p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt">
</p>
</td>
</tr>
</table></div>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Segment Information</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">Operating segments are defined as components of an enterprise about which separate discrete information is available for evaluation by the chief operating decision maker, or decision-making group, in deciding how to allocate resources and in assessing performance. We view our operations and manage our business in one segment, which is the identification and development of neuropsychiatric therapeutics.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
236000
698000
P4Y
P4Y
0.00
0.00
P6Y3M
P5Y
P6Y22D
P5Y6M
1.180
1.039
0.8608
0.7766
0.0175
0.0084
0.0198
0.0175
6740000
764338
1.75
P7Y4M24D
P10Y
P10Y
170659
54000
589719
700000
0.85
6.09
10357000
689663
1093208
700000
970574
1670574
1.04
4.37
P8Y7M6D
10357000
1670574
4.37
1.04
1.04
8.99
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Stock-Based Compensation</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">We account for stock-based compensation in accordance with the provisions of Accounting Standards Codification (ASC) Topic 718, Compensation—Stock Compensation, or ASC 718, which requires the recognition of expense related to the fair value of stock-based awards in the statements of operations. For stock options issued to employees and members of our board of directors for their services on our board of directors, we estimate the grant-date fair value of options using the Black-Scholes option pricing model. The use of the Black-Scholes option pricing model requires management to make assumptions with respect to the expected term of the option, the expected volatility of the common stock consistent with the expected life of the option, risk-free interest rates, and the value of the common stock. For awards subject to time-based vesting, we recognize stock-based compensation expense, net of estimated forfeitures, on a straight-line basis over the requisite service period, which is generally the vesting term of the award. For awards subject to performance-based vesting conditions, we recognize stock-based compensation expense when it is probable that the performance condition will be achieved. Stock-based awards issued to non-employees are recorded at their fair values, and are periodically revalued as the equity instruments vest and are recognized as expense over the related service period in accordance with the provisions of ASC 718 and ASC Topic 505, Equity.</font>
</p>
<p style="margin:0pt;text-align:center;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
8
1.51
0.63
1.1845
478745
29231
494260
29231
14036985
29231
-55365000
867000
1000
-56233000
-60381000
1121000
1000
-61503000
41154000
113476000
14000
-72336000
0.154
500000
7661871
220
5758000
422119
5758000
15515
15515
122634
122634
41202000
41196000
6000
18000
18000
128000
128000
2600000
400000
30596000
17929000
11023000
30596000
17929000
21314000
0.001
0.001
0.001
18777860
15275824
18900000
18777860
12220661
18381463
18777860
12220661
9654443
18777860
12220661
18381463
10291000
500000
29231
29231
0
<div> <div style="margin-left:0pt;margin-right:0pt;">
<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;font-weight:bold;">Use of Estimates</font>
</p>
<p style="margin:0pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;">The preparation of financial statements in conformity with generally accepted accounting principles (GAAP) requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from such estimates.</font>
</p>
<p style="margin:0pt;text-indent:36pt;line-height:normal;font-family:Times New Roman;font-size: 10pt">
<font style="display: inline;"> </font>
</p>
<p><font size="1"> </font></p>
</div> </div>
2300000
3900000
1192000
1192000
1192000
0
462972
6152669