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Property and Equipment (Details) (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Property and equipment    
Property and equipment, gross $ 400us-gaap_PropertyPlantAndEquipmentGross $ 445us-gaap_PropertyPlantAndEquipmentGross
Less: accumulated depreciation (356)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment (429)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
Property and equipment 44us-gaap_PropertyPlantAndEquipmentNet 16us-gaap_PropertyPlantAndEquipmentNet
Depreciation expense 5us-gaap_DepreciationAndAmortization 10us-gaap_DepreciationAndAmortization
Laboratory equipment    
Property and equipment    
Property and equipment, gross 326us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_EquipmentMember
369us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_EquipmentMember
Office equipment    
Property and equipment    
Property and equipment, gross $ 74us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_OfficeEquipmentMember
$ 76us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_OfficeEquipmentMember