144 0001276038 XXXXXXXX LIVE 0001267565 COLLEGIUM PHARMACEUTICAL, INC 001-37372 100 TECHNOLOGY CENTER DRIVE STOUGHTON MA 02072 781-713-3699 SANTINI GINO Director Common Fidelity Brokerage Services LLC

900 Salem Street Smithfield RI 02917

5405 201018.82 31502127 08/15/2025 NASDAQ Common 08/15/2025 Option Granted - 09/10/2015 Issuer N 5405 08/15/2025 Cash Y 08/15/2025 /s/ Tyler Johnson, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Gino Santini