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Stock-based Compensation (Tables)
9 Months Ended
Sep. 30, 2022
Stock-based Compensation  
Summary of performance share units activity

​

​

​

​

​

​

​

​

​

​

​

Weighted-Average

​

​

Shares

​

Grant Date Fair Value

Outstanding at December 31, 2021

​

353,100

​

$

31.77

Granted

​

241,550

​

​

24.12

Vested

​

(126,081)

​

​

29.12

Forfeited

​

(22,104)

​

​

29.60

Performance adjustment

​

1,305

​

​

28.96

Outstanding at September 30, 2022

​

447,770

​

$

28.71

Summary of restricted stock units activity

​

​

​

​

​

​

​

​

​

​

​

Weighted-Average

​

​

Shares

​

Grant Date Fair Value

Outstanding at December 31, 2021

​

1,620,023

​

$

22.48

Granted

​

1,272,497

​

​

17.48

Vested

​

(565,669)

​

​

21.93

Forfeited

​

(366,691)

​

​

20.58

Outstanding at September 30, 2022

​

1,960,160

​

$

19.75

Summary of stock option activity

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​

​

​

​

​

​

​

​

​

​

​

​

 

​

 

​

​

 

Weighted-

 

​

​

​

​

​

 

​

Weighted-

 

Average

​

​

​

​

​

​

 

​

Average

 

Remaining

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​

Aggregate

​

​

​

​

​

Exercise Price

 

Contractual

​

​

Intrinsic

​

    

Shares

    

​

per Share

    

Term (in years)

    

​

Value

Outstanding at December 31, 2021

 

2,728,169

​

$

18.33

 

5.8

​

$

6,070

Granted

 

—

​

​

—

​

​

​

​

​

Exercised

 

(302,752)

​

​

16.34

​

​

​

​

​

Cancelled

 

(268,916)

​

​

21.38

​

​

​

​

​

Outstanding at September 30, 2022

 

2,156,501

​

$

18.23

 

5.4

​

$

2,142

Exercisable at September 30, 2022

 

1,969,414

​

$

18.18

​

5.2

​

$

2,023

Summary of stock-based compensation

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Three Months Ended September 30,

​

Nine Months Ended September 30,

​

2022

​

2021

​

2022

​

2021

Research and development

$

—

    

$

233

​

$

1,591

    

$

2,697

Selling, general and administrative

 

5,377

​

​

5,715

​

 

15,613

​

​

16,646

Total stock-based compensation expense

$

5,377

​

$

5,948

​

$

17,204

​

$

19,343