Stock-based Compensation (Tables)

6 Months Ended

Jun. 30, 2022

Stock-based Compensation

Summary of performance share units activity

		Weighted-Average
	Shares	Grant Date Fair Value
Outstanding at December 31, 2021	353,100	$	31.77
Granted	241,550		24.12
Vested	(126,081)		29.12
Forfeited	(22,104)		29.60
Performance adjustment	1,305		28.96
Outstanding at June 30, 2022	447,770	$	28.71

Summary of restricted stock units activity

		Weighted-Average
	Shares	Grant Date Fair Value
Outstanding at December 31, 2021	1,620,023	$	22.48
Granted	1,241,897		17.48
Vested	(548,025)		22.09
Forfeited	(289,261)		20.72
Outstanding at June 30, 2022	2,024,634	$	19.76

Summary of stock option activity

				Weighted-
			Weighted-	Average
			Average	Remaining		Aggregate
			Exercise Price	Contractual		Intrinsic
	Shares		per Share	Term (in years)		Value
Outstanding at December 31, 2021	2,728,169	$	18.33	5.8	$	6,070
Granted	—		—
Exercised	(292,357)		16.44
Cancelled	(204,917)		21.81
Outstanding at June 30, 2022	2,230,895	$	18.26	5.7	$	4,040
Exercisable at June 30, 2022	1,948,941	$	18.19	5.5	$	3,724

Summary of stock-based compensation

	Three Months Ended June 30,				Six Months Ended June 30,
	2022		2021		2022		2021
Research and development	$	—	$	1,248	$	1,591	$	2,465
Selling, general and administrative		5,692		5,268		10,236		10,930
Total stock-based compensation expense	$	5,692	$	6,516	$	11,827	$	13,395