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Goodwill and Intangible Assets - Future Amortization Expense (Details) - USD ($)
$ in Thousands
Mar. 31, 2022
Dec. 31, 2021
Finite-Lived Intangible Assets [Line Items]    
2022 $ 114,228  
2023 152,305  
2024 152,305  
2025 152,304  
2026 85,124  
Thereafter 38,533  
Intangible asset, net 694,799 $ 268,723
Nucynta Products    
Finite-Lived Intangible Assets [Line Items]    
2022 50,385  
2023 67,181  
2024 67,181  
2025 67,180  
Intangible asset, net 251,927 $ 268,723
Belbuca    
Finite-Lived Intangible Assets [Line Items]    
2022 58,115  
2023 77,487  
2024 77,487  
2025 77,487  
2026 77,487  
Intangible asset, net 368,063  
Symproic    
Finite-Lived Intangible Assets [Line Items]    
2022 5,464  
2023 7,285  
2024 7,285  
2025 7,285  
2026 7,285  
Thereafter 35,214  
Intangible asset, net 69,818  
Elyxyb    
Finite-Lived Intangible Assets [Line Items]    
2022 264  
2023 352  
2024 352  
2025 352  
2026 352  
Thereafter 3,319  
Intangible asset, net $ 4,991