Goodwill and Intangible Assets - Cost, accumulated amortization, and carrying amount of intangible assets and goodwill (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Dec. 31, 2021
Finite-Lived Intangible Assets [Line Items]
Goodwill	$ 131,512
Cost	966,170	$ 521,170
Accumulated amortization	(271,371)	(252,447)
Carrying Amount	$ 694,799	268,723
Nucynta Products
Finite-Lived Intangible Assets [Line Items]
Amortization Period (Years)	8 years
Cost	$ 521,170	521,170
Accumulated amortization	(269,243)	(252,447)
Carrying Amount	$ 251,927	$ 268,723
Belbuca
Finite-Lived Intangible Assets [Line Items]
Amortization Period (Years)	4 years 9 months 18 days
Cost	$ 370,000
Accumulated amortization	(1,937)
Carrying Amount	$ 368,063
Symproic
Finite-Lived Intangible Assets [Line Items]
Amortization Period (Years)	9 years 7 months 6 days
Cost	$ 70,000
Accumulated amortization	(182)
Carrying Amount	$ 69,818
Elyxyb
Finite-Lived Intangible Assets [Line Items]
Amortization Period (Years)	14 years 2 months 12 days
Cost	$ 5,000
Accumulated amortization	(9)
Carrying Amount	$ 4,991