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License Agreements (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Jan. 09, 2018
Nov. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
License Agreements [Line Items]            
Cost of product revenues     $ 46,754 $ 46,007 $ 144,572 $ 135,951
Annual net sales     $ 72,942 $ 70,176 $ 222,498 $ 206,986
Exercise price of warrant   $ 19.20        
Nucynta Commercialization Agreement | Assertio            
License Agreements [Line Items]            
Cost of product revenues $ 10,000          
Annual net sales 135,000          
Nucynta Commercialization Agreement | Nucynta | Assertio            
License Agreements [Line Items]            
Payment for inventory 6,223          
Reimbursement for prepaid expenses 1,987          
Liability relating to sales 22,660          
Variable royalty payment based on net sales 233,000          
Quarterly royalty payable $ 33,750          
Nucynta Commercialization Agreement | Nucynta | Assertio | Sales Royalty Structure 1 [member]            
License Agreements [Line Items]            
Royalty payment as percentage of annual net sales on and after January 1, 2022   58.00%        
Nucynta Commercialization Agreement | Nucynta | Assertio | Sales Royalty Structure 2 [member]            
License Agreements [Line Items]            
Royalty payment as percentage of annual net sales on and after January 1, 2022   25.00%        
Nucynta Commercialization Agreement | Nucynta | Assertio | Sales Royalty Structure 3 [member]            
License Agreements [Line Items]            
Royalty payment as percentage of annual net sales on and after January 1, 2022   17.50%        
Royalty payment limit on and after January 1, 2022   $ 258,000        
Nucynta Commercialization Agreement | Nucynta | Assertio | Minimum | Sales Royalty Structure 2 [member]            
License Agreements [Line Items]            
Royalty payment limit on and after January 1, 2022   233,000        
Nucynta Commercialization Agreement | Nucynta | Assertio | Maximum | Sales Royalty Structure 1 [member]            
License Agreements [Line Items]            
Royalty payment limit on and after January 1, 2022   233,000        
Nucynta Commercialization Agreement | Nucynta | Assertio | Maximum | Sales Royalty Structure 2 [member]            
License Agreements [Line Items]            
Royalty payment limit on and after January 1, 2022   $ 258,000        
Third Amendment to the Commercialization Agreement            
License Agreements [Line Items]            
Number of shares that can be purchased   1,041,667        
Exercise price of warrant   $ 19.20        
Third Amendment to the Commercialization Agreement | Nucynta            
License Agreements [Line Items]            
Minimum royalty payment eliminated   $ 135,000        
Third Amendment to the Commercialization Agreement | Nucynta | Maximum | Any 12-month period through January 1, 2022            
License Agreements [Line Items]            
Net sales limit upon which Counterparty can terminate without penalty   180,000        
Third Amendment to the Commercialization Agreement | Nucynta | Maximum | Any 12-month period commencing on January 1, 2022            
License Agreements [Line Items]            
Net sales limit upon which Counterparty can terminate without penalty   170,000        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio            
License Agreements [Line Items]            
Termination fee owed if Company terminates   $ 5,000        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Sales Royalty Structure 1 [member]            
License Agreements [Line Items]            
Royalty payment as percentage of annual net sales between January 1, 2019 and December 31, 2021   65.00%        
Royalty payment limit between January 1, 2019 and December 31, 2021   $ 180,000        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Sales Royalty Structure 2 [member]            
License Agreements [Line Items]            
Royalty payment as percentage of annual net sales between January 1, 2019 and December 31, 2021   14.00%        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Sales Royalty Structure 3 [member]            
License Agreements [Line Items]            
Royalty payment as percentage of annual net sales between January 1, 2019 and December 31, 2021   58.00%        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Sales Royalty Structure 4 [member]            
License Agreements [Line Items]            
Royalty payment as percentage of annual net sales between January 1, 2019 and December 31, 2021   20.00%        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Sales Royalty Structure 5 [member]            
License Agreements [Line Items]            
Royalty payment as percentage of annual net sales between January 1, 2019 and December 31, 2021   15.00%        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Minimum | Sales Royalty Structure 2 [member]            
License Agreements [Line Items]            
Royalty payment limit between January 1, 2019 and December 31, 2021   $ 180,000        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Minimum | Sales Royalty Structure 3 [member]            
License Agreements [Line Items]            
Royalty payment limit between January 1, 2019 and December 31, 2021   210,000        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Minimum | Sales Royalty Structure 4 [member]            
License Agreements [Line Items]            
Royalty payment limit between January 1, 2019 and December 31, 2021   233,000        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Minimum | Sales Royalty Structure 5 [member]            
License Agreements [Line Items]            
Royalty payment limit between January 1, 2019 and December 31, 2021   258,000        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Minimum | Sales Royalty Structure 6 [member]            
License Agreements [Line Items]            
Sales threshold where supplemental royalty payment is due   $ 180,000        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Maximum            
License Agreements [Line Items]            
Percentage of supplemental royalty based on net sales   4.90%        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Maximum | Sales Royalty Structure 2 [member]            
License Agreements [Line Items]            
Royalty payment limit between January 1, 2019 and December 31, 2021   $ 210,000        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Maximum | Sales Royalty Structure 3 [member]            
License Agreements [Line Items]            
Royalty payment limit between January 1, 2019 and December 31, 2021   233,000        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Maximum | Sales Royalty Structure 4 [member]            
License Agreements [Line Items]            
Royalty payment limit between January 1, 2019 and December 31, 2021   258,000        
Third Amendment to the Commercialization Agreement | Nucynta | Assertio | Maximum | Sales Royalty Structure 6 [member]            
License Agreements [Line Items]            
Sales threshold where supplemental royalty payment is due   $ 243,000