SCHEDULE 13G/A 0001085146-24-005627 0000769734 XXXXXXXX LIVE 1 Common stock, par value $0.001 per share 06/30/2025 0001267565 COLLEGIUM PHARMACEUTICAL, INC 19459J104 100 TECHNOLOGY CENTER DRIVE STOUGHTON MA 02072 Rule 13d-1(b) PRINCIPAL GLOBAL INVESTORS DE 0 1466506 0 1466506 1466506 N 4.6 IA COLLEGIUM PHARMACEUTICAL, INC 100 TECHNOLOGY CENTER DRIVE, STOUGHTON, MASSACHUSETTS 02072 PRINCIPAL GLOBAL INVESTORS 711 HIGH STREET DES MOINES, Iowa 50392-0300 PRINCIPAL GLOBAL INVESTORS - DELAWARE N IA 1,466,506 4.6 PRINCIPAL GLOBAL INVESTORS - 0 PRINCIPAL GLOBAL INVESTORS - 1,466,506 PRINCIPAL GLOBAL INVESTORS - 0 PRINCIPAL GLOBAL INVESTORS - 1,466,506 N Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. PRINCIPAL GLOBAL INVESTORS /s/ J. Markham Penrod 08/08/2025