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Related Party Transactions (Details Narrative) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Dec. 11, 2013
May 31, 2011
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Scientific research cost     $ 1 $ 1    
Exercise of stock options to purchase shares amount     $ 481 $ 2,782 $ 506  
Forgiveness of notes receivable from an officer for stock option exercises         $ 423 $ 423
Robert J. Greenberg [Member]            
Exercise of stock options to purchase shares 200,000 100,000        
Exercise of stock options to purchase shares amount $ 100 $ 319        
Exercise of stock options to purchase shares expiration date Dec. 31, 2018 May 31, 2016        
Exercise of stock options to purchase shares interest rate 1.64% 2.26%