Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2015

Accounting Policies [Abstract]

Schedule of estimated useful life of property and equipment

Estimated useful lives of the principal classes of assets are as follows:

Lab equipment	5 – 7 years
Computer hardware and software	3 – 7 years
Leasehold improvements	2 – 5 years or the term of the lease, if shorter
Furniture, fixtures and equipment	5 – 10 years

Schedule of customer concentration of risk in revenue

During the years ended December 31, 2016, 2015 and 2014, the following customers comprised more than 10% of revenues:

	2016			2015			2014
Customer 1		13	%		14	%		7	%
Customer 2		3	%		4	%		10	%
Customer 3		2	%		7	%		21	%

Schedule of customer concentration of risk in accounts receivable

As of December 31, 2016 and 2015, the following customers comprised more than 10% accounts receivable:

	2016			2015
Customer 1		34	%		1	%
Customer 2		34	%		0	%
Customer 3		29	%		0	%
Customer 4		0	%		19	%
Customer 5		0	%		17	%
Customer 6		0	%		10	%
Customer 7		0	%		10	%
Customer 8		0	%		10	%

Schedule of geographic concentration of risk in revenue

During the years ended December 31, 2016, 2015 and 2014, regional revenue, based on customer locations which comprised more than 10% of revenues, consisted of the following:

	2016			2015			2014
United States		47	%		46	%		47	%
Italy		17	%		20	%		8	%
Germany		12	%		6	%		16	%
France		9	%		16	%		3	%
Canada		3	%		5	%		10	%

Schedule of net loss per share

At December 31, 2016, 2015 and 2014, the Company excluded the outstanding securities summarized below, which entitle the holders thereof to ultimately acquire shares of common stock, from its calculation of earnings per share, as their effect would have been anti-dilutive (in thousands).

	2016		2015		2014
Long Term Investor Rights		—		400		1,021
Underwriter’s warrants		802		802		805
Warrants associated with convertible debt		1,039		1,039		1,179
Common stock options		3,667		3,472		3,251
Restricted stock units		131		190		—
Employee stock purchase plan		206		93		—
Total		5,845		5,996		6,256