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Helsinn License Agreement - Additional Information (Detail) - USD ($)
Mar. 31, 2017
Aug. 31, 2016
Potential Regulatory and Sales-Based Milestone Payment | Maximum    
Related Party Transaction [Line Items]    
Milestone payment receivable amount   $ 444,000,000
Helsinn License Agreement | Helsinn    
Related Party Transaction [Line Items]    
Compensation receivable for grant of rights   20,000,000
Helsinn License Agreement | Helsinn | Payment in August 2016    
Related Party Transaction [Line Items]    
Compensation receivable for grant of rights   $ 15,000,000
Helsinn License Agreement | Helsinn | Balance Payment    
Related Party Transaction [Line Items]    
Compensation receivable for grant of rights $ 5,000,000