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License Agreements - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended
Sep. 30, 2017
Sep. 30, 2021
Sep. 30, 2020
Jun. 30, 2021
May 31, 2020
Related Party Transaction [Line Items]          
Milestone payment receivable amount   $ 10,000,000.0      
Milestone payments payable amount   20,000,000.0      
Expected milestone payment receivable   10,000,000.0      
Revenue recognised   417,000 $ (1,718,000)    
Kyowa Kirin Co          
Related Party Transaction [Line Items]          
Total upfront payment receivable for grant of rights         $ 100,000,000.0
Kyowa Kirin Co | Potential Payments on Achievement of Development Regulatory and Commercial Milestones | Maximum          
Related Party Transaction [Line Items]          
Milestone payment receivable amount   582,500,000      
Presage License Agreement | Presage Biosciences, Inc.          
Related Party Transaction [Line Items]          
Compensation payable for grant of rights $ 4,900,000        
Payment for license 2,900,000        
Presage License Agreement | Presage Biosciences, Inc. | Incremental Payment          
Related Party Transaction [Line Items]          
Compensation payable for grant of rights 2,000,000.0        
Presage License Agreement | Presage Biosciences, Inc. | Potential Payments on Achievement of Development Regulatory and Commercial Milestones          
Related Party Transaction [Line Items]          
Milestone payment receivable amount $ 179,000,000        
Kkc Agreements [Member] | Kyowa Kirin Co          
Related Party Transaction [Line Items]          
Upfront payment   100,000,000.0      
Transaction price relating to the performance obligation   191,500,000      
Expected milestone payment receivable   20,000,000.0      
Estimated development cost sharing recovered through earnings   66,300,000      
Deferred revenue   5,200,000      
Kkc Agreements [Member] | Kyowa Kirin Co | Ex US License          
Related Party Transaction [Line Items]          
Revenue recognised   21,000,000.0      
License Obligation Account Transaction Price Allocated   64,500,000      
Kkc Agreements [Member] | Kyowa Kirin Co | Development Services          
Related Party Transaction [Line Items]          
Contract with customer liability non current   35,100   $ 14,700  
Kkc Agreements [Member] | Kyowa Kirin Co | Maximum          
Related Party Transaction [Line Items]          
Estimated development cost sharing recovered through earnings   $ 280,700,000