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Equity Incentive Plans - Stock Option Activity (Details) - Common stock options - $ / shares
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Dec. 29, 2023
Options        
Options outstanding at beginning of year (in shares) 7,928 5,183    
Options granted (in shares) 35,825 3,749    
Options exercised (in shares)   0    
Options cancelled/forfeited (in shares) (710) (1,004)    
Options outstanding at end of year (in shares) 43,043 7,928 5,183  
Options exercisable at end of year (in shares) 5,007      
Vested and expected to vest at end of year (in shares) 43,043      
Weighted Average Exercise Price        
Options outstanding at beginning of year (in dollars per share) $ 3,187.50 $ 5,666.50    
Options granted (in dollars per share) 2.64 198.50    
Options exercised (in dollars per share)   0    
Options cancelled/forfeited (in dollars per share) 2,398.42 4,872.00    
Options outstanding at end of year (in dollars per share) 548.70 $ 3,187.50 $ 5,666.50  
Options exercisable at end of year (in dollars per share) $ 4,438.73      
Weighted Average Remaining Contractual Life (Years)        
Options outstanding 9 years 7 years 8 months 12 days 6 years 1 month 6 days  
Options exercisable 5 years 9 months 18 days      
Estimated stock price (in dollars per share)       $ 1.95