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Stockholders' Equity - Common Stock (Details) - USD ($) $ / shares in Units, $ in Millions									1 Months Ended			3 Months Ended			9 Months Ended	12 Months Ended
	Aug. 22, 2022	Jul. 06, 2022	Apr. 27, 2022	Apr. 25, 2022	Apr. 04, 2022	Mar. 15, 2022	Mar. 14, 2022	Jan. 10, 2022	Jul. 31, 2022	Oct. 31, 2021	Mar. 31, 2021	Sep. 30, 2022	Jun. 30, 2022	Mar. 31, 2022	Sep. 30, 2022	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020	Mar. 22, 2022	Sep. 30, 2021	Feb. 28, 2021	Feb. 26, 2021	Feb. 10, 2021	Oct. 02, 2020	Feb. 10, 2020
Sale of stock
Common stock that can be purchased with warrants (in shares)										333,333				1,242,813
Stock stated value																$ 0.0001	$ 0.0001
Maximum
Sale of stock
Proceeds from issuance of common stock in public offering, net of offering costs	$ 75.0
Common stock
Sale of stock
Conversion of convertible preferred stock (in shares)					303,125
Perceptive Warrants \| Perceptive Credit Agreement
Sale of stock
Common stock that can be purchased with warrants (in shares)										35,000						35,000					11,250
Exercise price of warrants (in dollars per share)																						$ 114.80
First Seven Lakhs Shares \| Perceptive Credit Agreement
Sale of stock
Common stock that can be purchased with warrants (in shares)									17,500	17,500				17,500		17,500			17,500
Exercise price of warrants (in dollars per share)									$ 14.90	$ 141.60				$ 105.52						$ 186.80			$ 186.80		$ 149.60
Remaining Seven Lakhs Shares \| Perceptive Credit Agreement
Sale of stock
Common stock that can be purchased with warrants (in shares)									17,500	17,500				17,500		17,500
Exercise price of warrants (in dollars per share)									$ 12.37	$ 115.20				$ 86.61						149.60			$ 149.60		$ 186.80
Warrants \| Perceptive Credit Agreement
Sale of stock
Common stock that can be purchased with warrants (in shares)									11,250	11,250				11,250
Exercise price of warrants (in dollars per share)									$ 10.03	$ 90.80				$ 69.13						$ 114.80		$ 114.80
Series A-1 warrants
Sale of stock
Warrant Exercisable Term		5 years
Series A-2 warrants
Sale of stock
Exercisable term		13 months
Series B Warrants
Sale of stock
Conversion of stock shares converted						303,125
2020 Shelf Registration Statement
Sale of stock
Aggregate amount of securities issuable																								$ 200.0
2022 Preferred Stock Offering
Sale of stock
Common stock that can be purchased with warrants (in shares)							30,313
Proceeds from issuance of common stock in public offering, net of offering costs							$ 4.1
Exercise price of warrants (in dollars per share)							$ 10.00
Conversion price							$ 8.00
Preferred Stock, convertible, shares issuable							606,250
Exercisable term							6 months
Stock stated value							$ 1,000
Warrants and rights outstanding, term							5 years
Duration From Offering To Anniversary Of Closing				180 days
2022 Preferred Stock Offering \| Series A Warrants
Sale of stock
Common stock that can be purchased with warrants (in shares)				212,188			606,250
Exercise price of warrants (in dollars per share)				$ 10.40			$ 10.40
Exercisable term							6 months
Warrants and rights outstanding, term							5 years
Warrant Exercisable Term				5 years
2022 Preferred Stock Offering \| Series B Warrants
Sale of stock
Common stock that can be purchased with warrants (in shares)							606,250
Exercise price of warrants (in dollars per share)							$ 10.40
Exercisable term							6 months
Warrants and rights outstanding, term							1 year 6 months
At-the-market sales \| Common stock
Sale of stock
Issuance of common stock (in shares)											172,879	26,666,666	8,687,502	25,623		12,655,773	172,879
Proceeds from issuance of common stock in public offering, net of offering costs																	$ 9.3
At-the-market sales \| Common stock \| Maximum
Sale of stock
Commission percentage											3.00%
Authorized value for shares issuance											$ 50.0
Public offering
Sale of stock
Issuance of common stock (in shares)		7,518,334							7,518,334
Common stock that can be purchased with warrants (in shares)		7,518,334							38,296,664	333,333
Share price (in dollars per share)									$ 0.90
Proceeds from issuance of common stock in public offering, net of offering costs		$ 22.0
Public offering \| Common stock
Sale of stock
Issuance of common stock (in shares)		19,148,332							19,148,332	666,666						26,666,666	666,666	431,250
Common stock that can be purchased with one-half of warrant (in shares)										1
Share price (in dollars per share)									$ 0.8999	$ 34.00
Proceeds from issuance of common stock in public offering, net of offering costs									$ 22.0	$ 21.1
Public offering \| Warrants
Sale of stock
Common stock that can be purchased with warrants (in shares)									15,036,668
Public offering \| Pre-funded warrants
Sale of stock
Common stock that can be purchased with warrants (in shares)									7,518,334
2022 ATM
Sale of stock
Issuance of common stock (in shares)															8,687,502	3,942,648
Proceeds from issuance of common stock in public offering, net of offering costs															$ 12.2	$ 0.9
2022 ATM \| Common stock
Sale of stock
Issuance of common stock (in shares)															25,623
Proceeds from issuance of common stock in public offering, net of offering costs															$ 0.3
2022 ATM \| Common stock \| Maximum
Sale of stock
Commission percentage								3.00%
Authorized value for shares issuance								$ 50.0
2022 ATM \| New Warrant [Member]
Sale of stock
Warrant Exercisable Term				6 months
H.C. Wainwright & Co., LLC, Sales Agent [Member]
Sale of stock
Common stock that can be purchased with warrants (in shares)		1,333,333
Commission percentage		7.00%	3.00%
Exercise price of warrants (in dollars per share)		$ 1.125
H.C. Wainwright & Co., LLC, Sales Agent [Member] \| Common stock
Sale of stock
Issuance of common stock (in shares)			12,841,000
Series A Preferred Stock
Sale of stock
Conversion of stock shares converted						2,425
Series A Preferred Stock \| 2022 Preferred Stock Offering
Sale of stock
Issuance of common stock (in shares)							2,425
Series B Preferred Stock
Sale of stock
Issuance of common stock (in shares)					2,425
Series B Preferred Stock \| 2022 Preferred Stock Offering
Sale of stock
Issuance of common stock (in shares)							2,425