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Statements of Changes in Stockholders' Equity - USD ($)
Preferred Stock
Series A Convertible Preferred Stock
Preferred Stock
Series B Convertible Preferred Stock
Preferred Stock
Series A and B Convertible Preferred Stock
Preferred Stock
Common stock
Public offering
Common stock
At-the-market sales
Common stock
Series A Convertible Preferred Stock
Common stock
Series B Convertible Preferred Stock
Common stock
Additional Paid in Capital.
Public offering
Additional Paid in Capital.
At-the-market sales
Additional Paid in Capital.
Accumulated Other Comprehensive Income
Accumulated Deficit
Public offering
At-the-market sales
Total
Balance at Dec. 31, 2019                       $ 306,115,000   $ (260,370,000)     $ 45,745,000
Balance (in shares) at Dec. 31, 2019                 1,745,264                
Increase (decrease) in stockholders' equity                                  
Share-based compensation - stock options and RSUs                       2,818,000         2,818,000
Issuance of common stock                   $ 48,435,000         $ 48,435,000    
Issuance of common stock (in shares)         431,250                        
Issuance of common stock upon exercise of options                       610,000         610,000
Issuance of common stock upon exercise of options (in shares)                 12,586                
Warrants issued in connection with long-term debt                       3,570,000         3,570,000
Unrealized net gain on marketable securities                         $ 3,000       3,000
Net loss                           (51,853,000)     (51,853,000)
Balance at Dec. 31, 2020                       361,548,000 3,000 (312,223,000)     49,328,000
Balance (in shares) at Dec. 31, 2020                 2,189,100                
Increase (decrease) in stockholders' equity                                  
Share-based compensation - stock options and RSUs                       3,338,000         3,338,000
Issuance of common stock                   $ 11,898,000 $ 9,266,000       11,898,000 $ 9,266,000  
Issuance of common stock (in shares)         666,666 172,879                      
Issuance of common stock upon exercise of options                       75,000         75,000
Issuance of common stock upon exercise of options (in shares)                 3,160                
Vesting of RSUs (in shares)                 3,096                
Warrants issued in connection with long-term debt                       1,080,000         1,080,000
Unrealized net gain on marketable securities                         $ (3,000)       (3,000)
Net loss                           (71,067,000)     (71,067,000)
Balance at Dec. 31, 2021                       387,205,000   (383,290,000)     3,915,000
Balance (in shares) at Dec. 31, 2021                 3,034,901                
Increase (decrease) in stockholders' equity                                  
Share-based compensation - stock options and RSUs                       764,000         764,000
Issuance of common stock                     348,000         348,000  
Issuance of common stock (in shares)           25,623                      
Conversion of convertible preferred stock (in shares) (2,425)   4,850       303,125                    
Vesting of RSUs (in shares)                 1,773                
Net loss                           (10,385,000)     (10,385,000)
Balance at Mar. 31, 2022                       388,317,000   (393,675,000)     (5,358,000)
Balance (in shares) at Mar. 31, 2022       2,425         3,365,422                
Balance at Dec. 31, 2021                       387,205,000   (383,290,000)     3,915,000
Balance (in shares) at Dec. 31, 2021                 3,034,901                
Increase (decrease) in stockholders' equity                                  
Net loss                                 (15,553,000)
Balance at Jun. 30, 2022                 $ 1,000     401,211,000   (398,843,000)     2,369,000
Balance (in shares) at Jun. 30, 2022                 12,360,157                
Balance at Dec. 31, 2021                       387,205,000   (383,290,000)     3,915,000
Balance (in shares) at Dec. 31, 2021                 3,034,901                
Increase (decrease) in stockholders' equity                                  
Net loss                                 (21,481,000)
Balance at Sep. 30, 2022                 $ 4,000     401,744,000         (3,025,000)
Balance (in shares) at Sep. 30, 2022                 39,026,823                
Balance at Dec. 31, 2021                       387,205,000   (383,290,000)     3,915,000
Balance (in shares) at Dec. 31, 2021                 3,034,901                
Increase (decrease) in stockholders' equity                                  
Share-based compensation - stock options and RSUs                       2,492,000         2,492,000
Fractional shares retired as a result of reverse split                 (11)                
Issuance of common stock         $ 3,000 $ 1,000         13,456,000       $ 3,000 13,457,000  
Issuance of common stock (in shares)         26,666,666 12,655,773                      
Conversion of convertible preferred stock (in shares) (2,425) (2,425) 4,850       303,125 303,125                  
Vesting of RSUs (in shares)                 6,555                
Net loss                           (25,412,000)     (25,412,000)
Balance at Dec. 31, 2022                 $ 4,000     403,153,000   (408,702,000)     (5,545,000)
Balance (in shares) at Dec. 31, 2022                 42,970,134                
Balance at Mar. 31, 2022                       388,317,000   (393,675,000)     (5,358,000)
Balance (in shares) at Mar. 31, 2022       2,425         3,365,422                
Increase (decrease) in stockholders' equity                                  
Share-based compensation - stock options and RSUs                       669,000         669,000
Fractional shares retired as a result of reverse split                 (10)                
Issuance of common stock           $ 1,000         12,225,000         $ 12,226,000  
Issuance of common stock (in shares)           8,687,502                      
Conversion of convertible preferred stock   $ (2,425)                              
Conversion of convertible preferred stock (in shares)               303,125                  
Vesting of RSUs (in shares)                 4,118                
Net loss                           (5,168,000)     (5,168,000)
Balance at Jun. 30, 2022                 $ 1,000     401,211,000   $ (398,843,000)     2,369,000
Balance (in shares) at Jun. 30, 2022                 12,360,157                
Increase (decrease) in stockholders' equity                                  
Share-based compensation - stock options and RSUs                       536,000          
Issuance of common stock           $ 3,000         $ (3,000)            
Issuance of common stock (in shares)           26,666,666                      
Net loss                                 (5,930,000)
Balance at Sep. 30, 2022                 $ 4,000     $ 401,744,000         $ (3,025,000)
Balance (in shares) at Sep. 30, 2022                 39,026,823