Organization and Description of Business (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Sep. 30, 2022	Jun. 30, 2022	Mar. 31, 2022	Dec. 31, 2021
Nature of Operations
Accumulated deficit	$ 408,702	$ 404,773	$ 398,843	$ 393,675	$ 383,290
Cash, cash equivalents and marketable securities	5,200
Working capital deficit	$ 2,000