Statements of Changes in Stockholders' Equity - USD ($) $ in Thousands	Preferred Stock Series A Convertible Preferred Stock	Preferred Stock Series B Convertible Preferred Stock	Preferred Stock Series A and B Convertible Preferred Stock	Preferred Stock	Common stock At-the-market sales	Common stock Series A Convertible Preferred Stock	Common stock Series B Convertible Preferred Stock	Common stock	Additional Paid in Capital. At-the-market sales	Additional Paid in Capital. Series A Convertible Preferred Stock	Additional Paid in Capital. Series B Convertible Preferred Stock	Additional Paid in Capital.	Accumulated Other Comprehensive Income	Accumulated Deficit	At-the-market sales	Series A and B Convertible Preferred Stock	Total
Balance at Dec. 31, 2020												$ 361,548	$ 3	$ (312,223)			$ 49,328
Balance (in shares) at Dec. 31, 2020								2,189,094
Increase (decrease) in stockholders' equity
Share-based compensation - stock options and RSUs												742					742
Issuance of common stock									$ 960						$ 960
Issuance of common stock (in shares)					13,023
Issuance of common stock upon exercise of options												75					75
Issuance of common stock upon exercise of options (in shares)								3,160
Vesting of RSUs (in shares)								1,316
Warrants issued in connection with long-term debt												1,080					1,080
Unrealized net gain on marketable securities													(3)				(3)
Net loss														(17,128)			(17,128)
Balance at Mar. 31, 2021												364,405		(329,351)			35,054
Balance (in shares) at Mar. 31, 2021								2,206,593
Balance at Dec. 31, 2020												361,548	$ 3	(312,223)			49,328
Balance (in shares) at Dec. 31, 2020								2,189,094
Increase (decrease) in stockholders' equity
Unrealized net gain on marketable securities																	(3)
Net loss																	(51,537)
Balance at Sep. 30, 2021												374,440		(363,760)			10,680
Balance (in shares) at Sep. 30, 2021								2,368,235
Balance at Mar. 31, 2021												364,405		(329,351)			35,054
Balance (in shares) at Mar. 31, 2021								2,206,593
Increase (decrease) in stockholders' equity
Share-based compensation - stock options and RSUs												843					843
Issuance of common stock									6,349						6,349
Issuance of common stock (in shares)					114,826
Vesting of RSUs (in shares)								1,786
Net loss														(17,637)			(17,637)
Balance at Jun. 30, 2021												371,597		(346,988)			24,609
Balance (in shares) at Jun. 30, 2021								2,323,205
Increase (decrease) in stockholders' equity
Share-based compensation - stock options and RSUs												887					887
Issuance of common stock									1,956						1,956
Issuance of common stock (in shares)					45,030
Net loss														(16,772)			(16,772)
Balance at Sep. 30, 2021												374,440		(363,760)			10,680
Balance (in shares) at Sep. 30, 2021								2,368,235
Balance at Dec. 31, 2021												396,388		(387,117)			9,271
Balance (in shares) at Dec. 31, 2021								3,034,901
Increase (decrease) in stockholders' equity
Share-based compensation - stock options and RSUs												764					764
Issuance of common stock									348						348
Issuance of common stock (in shares)					25,623
Registered direct financing costs, inclusive of warrants				$ (965)								244					(721)
Conversion of convertible preferred stock	$ (897)		$ 4,850							$ 897						$ 4,850
Conversion of convertible preferred stock (in shares)	(2,425)		4,850			303,125
Vesting of RSUs (in shares)								1,773
Warrants issued in connection with registered direct offering				(2,101)								2,101
Net loss														(11,769)			(11,769)
Balance at Mar. 31, 2022				$ 887								400,742		(398,886)			2,743
Balance (in shares) at Mar. 31, 2022				2,425				3,365,422
Balance at Dec. 31, 2021												396,388		(387,117)			9,271
Balance (in shares) at Dec. 31, 2021								3,034,901
Increase (decrease) in stockholders' equity
Net loss																	(43,652)
Balance at Sep. 30, 2022								$ 4				437,027		(430,771)			6,260
Balance (in shares) at Sep. 30, 2022								39,026,823
Balance at Mar. 31, 2022				$ 887								400,742		(398,886)			2,743
Balance (in shares) at Mar. 31, 2022				2,425				3,365,422
Increase (decrease) in stockholders' equity
Share-based compensation - stock options and RSUs												669					669
Fractional shares retired as a result of reverse split								(10)
Issuance of common stock					$ 1				12,225						12,226
Issuance of common stock (in shares)					8,687,502
Conversion of convertible preferred stock		$ (887)									$ 887
Conversion of convertible preferred stock (in shares)		(2,425)					303,125
Vesting of RSUs (in shares)								4,118
Net loss														(12,219)			(12,219)
Balance at Jun. 30, 2022								$ 1				414,523		(411,105)			3,419
Balance (in shares) at Jun. 30, 2022								12,360,157
Increase (decrease) in stockholders' equity
Share-based compensation - stock options and RSUs												536					536
Issuance of common stock					$ 3				$ 21,968						$ 21,971
Issuance of common stock (in shares)					26,666,666
Net loss														(19,666)			(19,666)
Balance at Sep. 30, 2022								$ 4				$ 437,027		$ (430,771)			$ 6,260
Balance (in shares) at Sep. 30, 2022								39,026,823