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Organization and Description of Business (Details) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Jul. 06, 2022
Jul. 31, 2022
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Oct. 31, 2021
Nature of Operations                
Accumulated deficit     $ 411,105,000   $ 411,105,000   $ 387,117,000  
Cash, cash equivalents and marketable securities     $ 13,000,000.0   13,000,000.0      
Working capital deficit         $ 10,300,000      
Common stock that can be purchased with warrants (in shares)     1,242,813   1,242,813     333,333
General and Administrative Expense     $ 3,026,000 $ 3,852,000 $ 7,023,000 $ 7,653,000    
Revision of Prior Period, Error Correction, Adjustment [Member]                
Nature of Operations                
General and Administrative Expense       $ (263,000)   $ (363,000)    
Subsequent Event | Series B Pre-funded Warrants                
Nature of Operations                
Common stock that can be purchased with warrants (in shares) 7,518,334              
Public offering                
Nature of Operations                
Proceeds from issuance of common stock and warrants $ 22,200,000              
Issuance of common stock (in shares) 19,148,332 7,518,334            
Common stock that can be purchased with warrants (in shares) 7,518,334 38,296,664           333,333
Public offering | Series B Pre-funded Warrants                
Nature of Operations                
Warrant shares issued 7,518,334