Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the reference to our firm under the caption “Experts” in the Registration Statement (Form S-3) and related Prospectus of Agile Therapeutics, Inc. for the registration of up to $200,000,000 of common stock, preferred stock, debt securities, warrants, rights to purchase common stock, preferred stock, debt securities or units and units and to the incorporation by reference therein of our report dated February 20, 2020, with respect to the financial statements of Agile Therapeutics, Inc.,  included in its Annual Report (Form 10-K) for the year ended December 31, 2019, filed with the Securities and Exchange Commission.

/s/ ERNST & YOUNG LLP

Iselin, New Jersey 

October 2, 2020