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Amount of increase in additional paid in capital (APIC) resulting from the issuance of warrants. Includes allocation of proceeds of debt securities issued with detachable stock purchase warrants.

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Exercise price per share or per unit of warrants or rights outstanding.

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Number of securities into which the class of warrant or right may be converted. For example, but not limited to, 500,000 warrants may be converted into 1,000,000 shares.

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Percentage points added to the reference rate to compute the variable rate on the debt instrument.

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The reference rate for the variable rate of the debt instrument, such as LIBOR or the US Treasury rate and the maturity of the reference rate used, such as three months or six months LIBOR.

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Amount of the fee that accompanies borrowing money under the debt instrument.

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Contractual interest rate for funds borrowed, under the debt agreement.

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Amount of payment greater than the preceding installment payments to be paid at final maturity date of debt.

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Amount, after accumulated amortization, of debt discount.

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Agreed upon price for the exchange of the underlying asset.

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Period the instrument, asset or liability is expected to be outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Risk-free interest rate assumption used in valuing an instrument.

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Amount of the cost of borrowed funds accounted for as interest expense for debt.

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Maximum borrowing capacity under the credit facility without consideration of any current restrictions on the amount that could be borrowed or the amounts currently outstanding under the facility.

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Amount of borrowing capacity currently available under the credit facility (current borrowing capacity less the amount of borrowings outstanding).

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Carrying value as of the balance sheet date of portion of long-term loans payable due within one year or the operating cycle if longer.

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The cash inflow from a debt initially having maturity due after one year or beyond the operating cycle, if longer.

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The cash inflow from the issuance of common stock, preferred stock, treasury stock, stock options, and other types of equity.

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Price of a single share of a number of saleable stocks of a company.

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Loan and Security Agreements - Oxford Loan and Hercules Loan (Details)	1 Months Ended	3 Months Ended		9 Months Ended
	Feb. 28, 2015 USD ($) $ / shares shares	Sep. 30, 2018 USD ($) $ / shares shares	Sep. 30, 2017 USD ($)	Sep. 30, 2018 USD ($) installment $ / shares shares	Sep. 30, 2017 USD ($)	Dec. 31, 2017 USD ($)	Aug. 31, 2016 USD ($)
Loan and Security Agreements
Outstanding borrowings, current portion		$ 5,905,000		$ 5,905,000		$ 10,607,000
Hercules Loan \| Hercules Capital, Inc. \| Equity financings \| Right to participate in future equity financings \| Maximum
Loan and Security Agreements
Equity financings amount	$ 2,000,000
Warrants \| Common stock warrants \| Hercules Capital, Inc.
Loan and Security Agreements
Common stock that can be purchased with warrants (in shares) \| shares	180,274	180,274		180,274
Exercise price of warrants (in dollars per share) \| $ / shares	$ 5.89	$ 5.89		$ 5.89
Significant assumptions used in preparing the option pricing model for valuing the Company's warrants
Volatility (as a percent)	75.00%
Risk free interest rate (as a percent)	1.22%
Life of treasury bonds	4 years
Strike price (in dollars per share) \| $ / shares	$ 5.89
Fair value of common stock (in dollars per share) \| $ / shares	$ 9.82
Expected life (in years)	4 years
Additional Paid-in Capital \| Hercules Capital, Inc.
Loan and Security Agreements
Fair value of common stock warrants issued with debt financing	$ 1,200,000
Warrants \| Common stock warrants \| Oxford Finance LLC
Loan and Security Agreements
Common stock that can be purchased with warrants (in shares) \| shares		62,505		62,505
Exercise price of warrants (in dollars per share) \| $ / shares		$ 6.00		$ 6.00
Secured debt
Loan and Security Agreements
Interest expense, including accretion of value of related warrants and amortization of deferred financing costs		$ 91	$ 459	$ 289	$ 1,509
Secured debt \| Oxford Loan \| Oxford Finance LLC
Loan and Security Agreements
Repayment of existing debt	15,500,000
Secured debt \| Hercules Loan \| Hercules Capital, Inc.
Loan and Security Agreements
Maximum borrowing capacity	25,000,000
Facility Fee							$ 165,000
Outstanding borrowings, current portion		$ 5,900,000		$ 5,900,000		$ 10,900,000
Fixed interest rate (as a percent)		9.00%		9.00%
Number of consecutive monthly principal installments \| installment				23
Final payment amount due		$ 611,000		$ 611,000
Prepayment premium as percentage of outstanding principal				1.00%
Discount on debt	1,200,000
Secured debt \| Hercules Loan Tranche One \| Hercules Capital, Inc.
Loan and Security Agreements
Amount borrowed	$ 16,500,000
Secured debt \| Hercules Loan Tranche Two \| Hercules Capital, Inc.
Loan and Security Agreements
Additional amount available		$ 8,500,000		$ 8,500,000
Secured debt \| Prime \| Hercules Loan \| Hercules Capital, Inc.
Loan and Security Agreements
Variable rate basis				Prime minus 4.25%
Variable interest rate margin (as a percent)				9.00%
Variable rate adjustment (as a percent)				(4.25%)