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Summary of Significant Accounting Policies - Net Loss Per Share (Details) - shares
9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Anti-dilutive securities    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 6,078,234 4,306,091
Common stock warrants    
Anti-dilutive securities    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 242,779 242,779
Unvested restricted stock units    
Anti-dilutive securities    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 147,554 264,361
Common stock options    
Anti-dilutive securities    
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 5,687,901 3,798,951